ArticleBrain communications2026
Field strength-dependent sensitivity of chemical exchange saturation transfer: a methodological comparison of 3 Tesla and 7 Tesla in a clinical cohort.
Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- BrainAgeMS: protocol for a prospective comparative study of brain aging in healthy adults and people with multiple sclerosis.Frontiers in neurology · 2026Observational
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11 authors.
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Abstract
Chemical exchange saturation transfer (CEST) MRI provides insight into tissue metabolism by detecting low-concentration endogenous molecules. While studies at 7 Tesla (7T) have shown enhanced sensitivity and spectral separation, 3 Tesla (3T) remains the clinical standard, and the relative performance of these field strengths in a direct clinical head-to-head comparison remains unclear. This prospective cohort study provides a direct within-subject comparison of multi-pool CEST imaging at 3T and 7T, using age-related tissue changes and glioma molecular subtypes as representative applications of physiological and pathological CEST sensitivity. Forty-three patients (ages 18-76; 18 female) underwent 3T and 7T CEST MRI prior to surgery due to suspected brain tumour; following quality control, 36 datasets were included at 3T and 32 at 7T. CEST amplitudes from amide, amine, aliphatic relayed nuclear Overhauser effect (rNOE) and magnetization transfer pools were quantified in white matter, grey matter, deep grey matter and tumour tissue. A physics-informed conditional autoencoder (PICAE) was applied at 7T to correct B
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