Evidence map›Paper›PMID 42428714›Full record

ArticleSisli Etfal Hastanesi tip bulteni2026

In Vitro Antimicrobial Activity of Five Turkish Honey Types Against Otitis Externa Pathogens: A Comparative Study.

Serdal Celik, Hamdi Sirac Gundogdu, Nihat Arda Buyukasik, Muhammed Yasir Gumustas, Merve Ozmen, Ayten Guner Atayoglu, Mücahide Esra Kocoglu, Mahmut Tayyar Kalcioglu

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Article in Sisli Etfal Hastanesi tip bulteni, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Serdal CelikDepartment of Otorhinolaryngology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Hamdi Sirac GundogduDepartment of Otorhinolaryngology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Nihat Arda BuyukasikDepartment of Otorhinolaryngology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Muhammed Yasir GumustasDepartment of Otorhinolaryngology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Merve OzmenDepartment of Medical Microbiology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Ayten Guner AtayogluDepartment of Family Medicine, Beylikduzu State Hospital, Istanbul, Türkiye.
Mücahide Esra KocogluDepartment of Medical Microbiology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Mahmut Tayyar KalciogluDepartment of Otorhinolaryngology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The global rise of antimicrobial resistance underscores the urgent need for alternative therapeutic agents for common infections such as otitis externa. This study aimed to investigate and compare the in vitro antimicrobial activity of five Turkish honey types-thyme, pine, linden, sunflower, and lavender-against eight microorganisms commonly associated with otitis externa. Methods: Honey samples were collected from certified Turkish beekeepers and analyzed for their physicochemical and biochemical properties. Antimicrobial activity was assessed using the broth microdilution method in line with CLSI guidelines. The tested microorganisms included Results: Thyme honey showed the broadest spectrum of antimicrobial activity (62.5%), with particularly low MICs against Conclusion: Turkish honey, especially thyme honey, demonstrates promising antibacterial activity against otitis externa pathogens. These findings suggest potential for honey-based adjunctive therapies in managing bacterial ear infections, particularly amid rising antibiotic resistance. However, the lack of antifungal efficacy highlights limitations in fungal otitis cases.

Indexed as

Antimicrobial resistancehoneynatural antimicrobial agentsotitis externaphenolic content

Identifiers

PMID42428714
PMCPMC13347724

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