Evidence map›Paper›PMID 42428706›Full record

ArticleSisli Etfal Hastanesi tip bulteni2026

Effects of Phototherapy on Sleep, Fatigue and Quality of Life in Dermatology Patients: A Pilot Study.

Hazel Ezgi Kaya, Asli Aksu, Pinar Ozdemir Cetinkaya, Birgul Ozkesici Kurt, Ali Tanakol, Ilknur Kivanc Altunay

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Article in Sisli Etfal Hastanesi tip bulteni, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hazel Ezgi KayaDepartment of Dermatology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Asli AksuDepartment of Dermatology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Pinar Ozdemir CetinkayaDepartment of Dermatology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Birgul Ozkesici KurtDepartment of Dermatology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Ali TanakolDepartment of Dermatology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Ilknur Kivanc AltunayDepartment of Dermatology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Sleep disturbances and fatigue are prevalent among dermatology patients. Owing to the growing evidence on the effects of light-based therapies on neuropsychiatric disorders, this study aimed to investigate how narrow-band ultraviolet B (NB-UVB) phototherapy influences sleep quality and fatigue. Methods: In this prospective observational study, 30 patients receiving or scheduled to receive NB-UVB phototherapy were included. Phototherapy was administered 2-3 times per week with eye protection. Sleep quality, fatigue, and dermatology-specific quality of life were assessed using the Pittsburgh Sleep Quality Index (PSQI), Piper Fatigue Scale (PFS), and Dermatology Life Quality Index (DLQI), respectively. Measurements were performed at study entry and at the one-month follow-up. Results: The mean age was 48.2±12.9 years, and 63.3% of the patients were male. The most common diagnoses were vitiligo (40%), mycosis fungoides (26.7%), and psoriasis vulgaris (13.3%). The median PSQI score decreased from 8 at baseline to 5 at the one-month follow-up (p<0.001). The median PFS score decreased from 3.88 to 2.38 (p=0.019). DLQI showed no significant change. Changes in PSQI and PFS were significantly correlated (r=0.435, p=0.016). Multiple regression analysis identified ΔPFS, total cumulative dose, and ΔDLQI as independent predictors of ΔPSQI. Conclusion: NB-UVB phototherapy was associated with improvements in sleep quality and fatigue in dermatology patients over the course of treatment. These effects appear to be independent of changes in dermatology-specific quality of life and are likely mediated through neuroendocrine, circadian, and peripheral pathways. NB-UVB phototherapy may serve as an effective adjunctive treatment for sleep disturbances and fatigue in dermatology patients.

Indexed as

DermatologyfatigueNB-UVBphototherapysleep quality

Identifiers

PMID42428706
PMCPMC13347725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.