ArticleAging medicine (Milton (N.S.W))2026
Lymph Node Metastasis Pattern and Influencing Factors in Esophageal Squamous Cell Carcinoma.
Article in Aging medicine (Milton (N.S.W)), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To investigate the lymph node metastasis (LNM) pattern of esophageal squamous cell carcinoma (ESCC) and identify factors associated with LNM. Methods: A retrospective study was conducted including 388 patients with ESCC who underwent curative resection at the First Affiliated Hospital of Nanjing Medical University between January 2020 and December 2022. Clinicopathological characteristics and lymph node metastasis patterns were analyzed. Univariate and multivariate analyses were performed to identify factors associated with LNM. Results: Among the 388 patients, 144 (37.11%) had lymph node metastasis. The total number of dissected lymph nodes was 8546, with 341 positive nodes, yielding an LNM degree of 3.99%. Upper thoracic ESCC was more likely to metastasize to upper right paratracheal lymph nodes, while lower thoracic ESCC showed a higher rate of paracardial lymph node metastasis. Tumor differentiation, tumor size, invasion depth, age, and intravascular tumor thrombus were associated with LNM. Multivariate logistic regression analysis revealed that tumor diameter ≥ 3 cm (OR = 2.485, 95% CI 1.483-4.165, Conclusions: Upper esophageal SCC tends to metastasize to upper mediastinal lymph nodes, whereas abdominal and paracardial lymph node metastasis is more common in lower esophageal SCC. Tumor size and intravascular tumor thrombus are independent risk factors for lymph node metastasis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.