Evidence map›Paper›PMID 42428681›Full record

ArticleAging medicine (Milton (N.S.W))2026

Effect of Lactulose on the Intestinal Flora of Elderly Constipation Patients With Chronic Renal Insufficiency.

Jianxia Ma, Jun Wang, Tianran Han, Zhifang Shao, Weiqi Zhang, Ke Wang, Qinlian Zeng, Kangwei Liu, Yuanwen Chen, Songbai Zhen and 1 more

Abstract read
In one paragraph

Article in Aging medicine (Milton (N.S.W)), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jianxia MaDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.
Jun WangDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.
Tianran HanShanghai Gonghui Hospital Shanghai China.
Zhifang ShaoShanghai Gonghui Hospital Shanghai China.
Weiqi ZhangShanghai Ren Shou Tang Wenjin Nursing Home Shanghai China.
Ke WangDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.
Qinlian ZengDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.
Kangwei LiuDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.
Yuanwen ChenDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.
Songbai ZhenDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.
Jianfeng YaoDepartment of Gastroenterology Hua Dong Hospital of Fu Dan University Shanghai China.ORCID https://orcid.org/0000-0001-6356-870X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the efficacy of lactulose in the treatment of elderly constipation patients with chronic renal insufficiency and its influence on renal function. Methods: They were divided into the lactulose group ( Results: Both lactulose and PEG could improve the symptoms of constipation, and no significant difference was observed ( Conclusion: Lactulose can improve renal function, mild inflammation, and gut microbiota in these patients. We speculate that the improvement of renal function after lactulose treatment may be related to the improvement of gut microbiota and systemic mild inflammation.

Indexed as

chronic constipationelderlygut microbiotalactuloserenal insufficiency

Identifiers

PMID42428681
PMCPMC13347155

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.