Evidence map›Paper›PMID 42428660›Full record

ReviewCardiovascular diagnosis and therapy2026

Diagnostic, cardiac imaging, and management considerations in fungal infective endocarditis: a contemporary narrative review.

Jan K Kalinski, Bo Xu

Abstract readReview
In one paragraph

Review in Cardiovascular diagnosis and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jan K KalinskiSection of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA.
Bo XuSection of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA.ORCID https://orcid.org/0000-0002-2985-7468

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Fungal infective endocarditis (FIE) is a rare but clinically important cause of endocarditis that poses unique challenges to diagnosis and treatment. As clinicians are faced with an aging population, increasing utilization of prosthetic valves and implantable cardiac devices, as well as increasing use of immunosuppressive therapies, which are known risk factors, familiarity with FIE is increasingly relevant. This narrative review presents the current state of knowledge concerning laboratory diagnosis, imaging tools, and treatment of FIE. Methods: A comprehensive literature search was conducted using PubMed between January 2000 and September 2025. Original research, reviews, meta-analyses, guideline documents, and consensus statements were considered. Individual case reports and non-English publications were excluded. Key Content and Findings: FIE is caused by a wide range of pathogens, with the most common etiological organisms being Conclusions: The prognosis of FIE continues to be poor, likely owing to difficulties that exist in both diagnosis and treatment. Broader awareness of the risk factors, nuanced diagnostic options and management considerations may serve to improve patient outcomes.

Indexed as

cardiac computed tomography (CT)cardiac surgeryechocardiographyFungal infective endocarditis (FIE)nuclear imaging

Identifiers

PMID42428660
PMCPMC13345793

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.