Evidence map›Paper›PMID 42428523›Full record

ArticlePeerJ2026

The RNA-binding protein Pumilio limits polymodal nociception in

Sara Palega, Hannah Davenport, Rebeccah K Stewart, Jessica Horton, Andrew Bellemer

Abstract read
In one paragraph

Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara PalegaBiomedical Sciences Program, Eastern Virginia Medical School, Norfolk, Virginia, United States.
Hannah DavenportDepartment of Biology, Appalachian State University, Boone, North Carolina, United States.
Rebeccah K StewartDepartment of Biology, Appalachian State University, Boone, North Carolina, United States.ORCID 0000-0002-9700-2250
Jessica HortonDepartment of Physics and Astronomy, Appalachian State University, Boone, North Carolina, United States.
Andrew BellemerDepartment of Biology, Appalachian State University, Boone, North Carolina, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Nociception is the process by which the nervous system detects and processes information about potentially harmful environmental stimuli to generate behavioral and physiological responses. The process of nociception undergoes plasticity in response to injury, inflammation, and infection to shape the sensitivity of nociceptive circuits and the behavioral responses they control. We are increasingly aware that post-transcriptional regulation of gene expression shapes the sensitivity and plasticity of nociceptive sensory neurons and nociceptive behavior. In

Indexed as

Drosophila melanogasterDrosophila ProteinsNociceptionNociceptorsRNA-Binding ProteinsAnimalsLarvaDrosophila Proteinspum protein, DrosophilaRNA-Binding ProteinsDrosophilaGene regulationNociceptionPumilio

Identifiers

PMID42428523
PMCPMC13348479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.