ArticleNeuro-oncology advances
Peritumoral brain zone oxygen extraction fraction is associated with tumor Ki-67 index in untreated glioblastoma.
Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Hypoxia-targeted BOLD MRI signal heterogeneity as a complementary metric for glioblastoma characterization: a pilot study.Journal of neuro-oncology · 2026Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The non-contrast-enhancing peritumoral brain zone (PBZ) contributes to glioblastoma progression but remains incompletely characterized by structural MRI. We tested whether PBZ oxygen extraction fraction (OEF) derived from dynamic susceptibility contrast (DSC) MRI is associated with the Ki‑67 proliferation index at the patient level. Methods: In this retrospective analysis, we analyzed 80 adults with untreated Results: PBZ OEF demonstrated a positive correlation with Ki-67 (Spearman ρ = 0.27, Conclusions: Higher DSC-derived PBZ OEF ratio was modestly but significantly associated with higher tumor Ki-67 in untreated
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