The hemodynamic effects of bolus norepinephrine and phenylephrine in the treatment of hypotensive events in preeclamptic women with severe features following spinal anesthesia during cesarean section: a randomized controlled trial.

Lili Zou, Hongping Li, Yongqiang Shi, Nan Xi, Yi Chen

Abstract read

In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lili Zou *Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.

Hongping Li *Department of Anesthesiology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital), Yinchuan, Ningxia, China.

Yongqiang ShiDepartment of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.

Nan XiDepartment of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.

Yi ChenDepartment of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study Objective: To investigate the hemodynamic effects of rescue bolus administration of norepinephrine (NE) and phenylephrine (PE) in the treatment of hypotensive events in preeclamptic women with severe features following spinal anesthesia during cesarean section. Methods: A total of 40 preeclamptic women with severe features ( Results: In the NE group, there was a lower magnitude of maximal changes (85.40 ± 17.76 vs. 71.10 ± 11.88 beats/min, Conclusion: Either 6 µg NE or 75 µg PE can effectively rescue and exhibit comparable efficacy in managing hypotensive events following spinal anesthesia in preeclamptic women with severe features. However, NE demonstrates superior capability in maintaining CO and HR.

Indexed as

cesarean sectionhemodynamic effectshypotensionnorepinephrinephenylephrinepreeclampsia with severe featuresspinal anesthesia

Identifiers

PMID42428501

DOI10.3389/fphar.2026.1783419

PMCPMC13346175

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.