Evidence map›Paper›PMID 42428499›Full record

ArticleFrontiers in pharmacology2026

From traditional remedy to

Adrian Strus, Weronika Skowrońska, Aleksandra Malarczyk, Maja Kirzyc, Jakub P Piwowarski, Marcin Równicki

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adrian StrusStudent Scientific Association "Herbarium", Department of Pharmaceutical Biology, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Weronika SkowrońskaDepartment of Pharmaceutical Biology, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Aleksandra MalarczykDepartment of Pharmaceutical Microbiology and Bioanalysis, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Maja KirzycMicrobiotaLab, Department of Pharmaceutical Microbiology and Bioanalysis, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Jakub P PiwowarskiMicrobiotaLab, Department of Pharmaceutical Microbiology and Bioanalysis, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Marcin RównickiMicrobiotaLab, Department of Pharmaceutical Microbiology and Bioanalysis, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Birch witches' broom is an abnormal plant structure caused by infection of birch trees with the dimorphic fungus Methods: Aqueous extracts from witches' broom and healthy birch branches were analyzed by UHPLC-DAD-MS Results: Phytochemical profiling revealed qualitative differences, particularly in flavonoids, phenolic acids, and diarylheptanoids. Cytotoxicity showed concentration-dependent effects. The IC Summary: This study provides the first direct comparison of their phytochemical composition and skin-related biological activity. The findings suggest that witches' broom contains bioactive compounds influencing cell viability, migration, and inflammation, supporting its potential relevance in dermatological research and ethnopharmacology.

Indexed as

BetulaethnopharmacologykeratinocytesSámiTaphrina betulinawitches’ broom

Identifiers

PMID42428499
PMCPMC13345859

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.