Evidence map›Paper›PMID 42428490›Full record

ArticleFrontiers in cardiovascular medicine2026

Surgical vs. trans-catheter aortic valve replacement in patients With bicuspid aortic valve stenosis.

Kobi Faierstein, Tal Caller, Dassi Moshkovitz, Efrat Sharon, Roy Raphael, Ido Cohen, Noam Makmal, Efrat Mazoe Dray, Afek Ash, Elad Maor and 4 more

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In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kobi FaiersteinLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Tal CallerLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Dassi MoshkovitzLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Efrat SharonLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Roy RaphaelLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Ido CohenLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Noam MakmalLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Efrat Mazoe DrayLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Afek AshLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Elad MaorLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Ehud RegevLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Amit SegevLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Israel M BarbashLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.
Paul FeferLeviev Cardiovascular Center, Sheba Medical Center, Ramat Gan, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aortic valve stenosis can be treated surgically or with transcatheter aortic valve implantation (TAVI). However, bicuspid aortic valve (BAV) anatomy presents unique challenges that may affect procedural outcomes. We aimed to compare outcomes between the two approaches. Methods: a retrospective cohort of 480 patients with BAV stenosis: 75 (16%) underwent TAVI and 405 (84%) underwent SAVR. Median age was 76 (Q1-Q3: 72-82) in the TAVI group and 61 (Q1-Q3: 52-70) in the SAVR group. Patients with isolated aortic insufficiency were excluded. Primary analyses were adjusted for age, sex, and comorbidities, followed by a sensitivity analysis using 1:1 age matching. Outcomes included overall survival, stroke/TIA, pacemaker implantation, paravalvular leak, and heart failure hospitalizations. Results: During a mean follow-up of 9 ± 5 years, 72 patients died (28 TAVI, 44 SAVR). TAVI was associated with higher mortality (adjusted HR = 5.9, 95% CI 2.6-12.9, Conclusions: In BAV stenosis, SAVR was associated with better survival and fewer complications than TAVI, while stroke/TIA rates were similar. Randomized trials are needed to determine the optimal treatment approach.

Indexed as

bicuspid aortc valveheart failure hospitalizationmortalitypacemaker (PM)paravalular leak (PVL)SAVRstrokeTAVI

Identifiers

PMID42428490
PMCPMC13346055

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