Evidence map›Paper›PMID 42428454›Full record

ArticleGynecology and pelvic medicine2026

Forty-month durable partial response with well-tolerated olaparib maintenance in a 92-year-old patient with

Xiaojuan Lin, Rui Li, Chuntang Sun, Mengpei Zhang, Jiacen Wan, Qingli Li

Abstract readCase Reports
In one paragraph

Article in Gynecology and pelvic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaojuan LinCancer Center, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0009-0001-5435-1100
Rui LiCancer Center, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.
Chuntang SunCancer Center, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.
Mengpei ZhangCancer Center, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.
Jiacen WanWest China School of Medicine, Sichuan University, Chengdu, China.
Qingli LiCancer Center, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-2290-4532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Treatment selection for very elderly patients with endometrial cancer (EC) is frequently constrained by multimorbidity and frailty, increasing the risk of undertreatment and compromised outcomes. With the incorporation of molecular profiling into clinical practice, a subset of ECs has been recognized to exhibit homologous recombination deficiency (HRD), providing a rationale for the use of poly(ADP-ribose) polymerase (PARP) inhibitors. However, evidence for PARP inhibitor maintenance in EC remains limited, particularly in nonagenarians. Case Description: A 92-year-old woman at first-time diagnosis of International Federation of Gynecology and Obstetrics (FIGO) stage IVB uterine serous carcinoma (USC) harboring a somatic Conclusions: This case illustrates that reduced-dose olaparib maintenance may be feasible and well-tolerated in very elderly patients with advanced,

Indexed as

BRCA mutationcase reportPoly(ADP-ribose) polymerase inhibitor (PARP inhibitor)uterine serous carcinoma (USC)very elderly patient

Identifiers

PMID42428454
PMCPMC13345791

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.