Evidence map›Paper›PMID 42428264›Full record

ArticleFrontiers in medicine2026

Infectious disease outcomes in end-stage renal disease: the influence of dialysis type on patient vulnerability in Hail region.

Rihab Akasha, Naif K Binsaleh, Randa Abdeen Husien Abdalla, Obey Suliman, Ibrahim Nasser Abuqurayn, Sultan Alouffi

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rihab AkashaDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia.
Naif K BinsalehDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia.
Randa Abdeen Husien AbdallaDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia.
Obey SulimanNephrology Consultant, King Khalid Hospital, Hail, Saudi Arabia.
Ibrahim Nasser AbuquraynNephrology Department Supervisor, Hail Cluster, Hail, Saudi Arabia.
Sultan AlouffiDepartment of Medical Laboratory Science, College of Applied Medical Sciences, University of Hail, Hail, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infections are a major threat to patients with end-stage renal disease (ESRD) receiving renal replacement therapy. Hemodialysis (HD) and peritoneal dialysis (PD) differ in access type, exposure to healthcare environments, and infection pathways, leading to distinct risks for catheter-related bloodstream infection (CRBSI), peritonitis, hospitalization, and adverse outcomes. Recognizing local patterns is essential for prevention planning and quality improvement. Aim: To compare dialysis-related infection prevalence, microbiological profiles, hospitalization events, and biochemical factors between HD and PD patients over a 3-year period (2023-2025) in a predominantly Saudi tertiary dialysis cohort, while describing overall documented infections and non-dialysis infection subtypes as secondary outcomes, and to identify potential infection risk factors relevant to local dialysis practice. Results: HD patients were older and had higher rates of diabetes and hypertension. Infection frequency was 18% in HD and 9% in PD. HD patients had higher incident rates of bloodstream infection, most of them catheter-related, whereas PD patients had higher peritonitis incidence. Infection-related hospitalization was higher in HD (12% vs. 6%), and CRP concentrations were higher in the period of infection. HD had a higher prevalence of Conclusion: HD patients had higher infection burden and more severe outcomes compared to PD patients. Prevention strategies specific to the modality, high-profile monitoring and high-performance quality improvement programs targeted to specific dialysis populations are required to reduce the complications arising from infection.

Indexed as

catheter-related bloodstream infectiondialysis outcomeshemodialysisinfectionperitoneal dialysisperitonitis

Identifiers

PMID42428264
PMCPMC13347288

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