Evidence map›Paper›PMID 42428214›Full record

ArticleCureus2026

Normoglycemic High Anion Gap Metabolic Acidosis With Hyperkalemia: An Unusual Presentation of Alcoholic Ketoacidosis.

Armaan Mishra, Mohammad Shagil, Lakhan Singh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Armaan MishraInternal Medicine, Rajmata Shrimati Devendra Kumari Singhdeo Government Medical College Ambikapur, Ambikapur, IND.
Mohammad ShagilInternal Medicine, Rajmata Shrimati Devendra Kumari Singhdeo Government Medical College Ambikapur, Ambikapur, IND.
Lakhan SinghGeneral Medicine, Chhattisgarh Institute of Medical Sciences, Bilaspur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcoholic ketoacidosis (AKA) is a form of high anion gap metabolic acidosis characterized by ketosis, typically occurring in malnourished individuals after binge alcohol consumption. If not identified early, it can lead to life-threatening electrolyte disturbances and cardiac arrhythmias. A man in his fifties presented with altered mental status and shortness of breath. Arterial blood gas analysis revealed severe metabolic acidosis with a pH of 7.22, a bicarbonate level of 4.2 mmol/L, and normal lactate levels. Urine ketones were strongly positive (4+). Electrocardiography demonstrated tall T waves, and serum potassium was elevated at 5.8 mEq/L. The combination of recent binge alcohol use, normoglycemia, ketosis, and high anion gap metabolic acidosis suggested AKA. Prompt fluid resuscitation and electrolyte correction resulted in progressive clinical improvement, and the patient was discharged without complications. This case highlights the importance of considering AKA in normoglycemic patients presenting with high anion gap metabolic acidosis and ketosis, particularly those with a history of excessive alcohol consumption. Accurate differentiation from diabetic ketoacidosis is essential because management strategies differ significantly. It is further distinguished by significant hyperkalemia with electrocardiographic changes, an atypical presentation of AKA in which serum potassium levels are usually normal or low.

Indexed as

alcoholic ketoacidosisdiabetic ketoacidosishyperkalemiametabolic acidosisstarvation ketosis

Identifiers

PMID42428214
PMCPMC13346014

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.