Evidence map›Paper›PMID 42428212›Full record

ReviewCureus2026

Medications and Supplements Associated With Drug-Induced Glaucoma.

Tarek Hammadieh, Ali Istanaksai, Khaled Jama, Abdalla Ali, Eesa Siddiqui, Haidar Bilal

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tarek HammadiehMedicine, Epsom Hospital, Epsom, GBR.
Ali IstanaksaiMedicine, North Middlesex University Hospital, London, GBR.
Khaled JamaPsychiatry, St George's Hospital, London, GBR.
Abdalla AliGeneral Surgery, Whittington Hospital, London, GBR.
Eesa SiddiquiMedicine, Royal Free Hospital, London, GBR.
Haidar BilalElderly Medicine, Epsom Hospital, Epsom, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is a common condition that damages the optic nerve, usually as a result of an increase in intraocular pressure (IOP). It can be divided into two types: open-angle glaucoma (OAG) and acute angle-closure glaucoma (AACG). OAG is believed to occur due to dysfunction in aqueous outflow through the trabecular meshwork (TM) of the eye as it flows from the posterior to the anterior chamber. AACG manifests when a bulging iris blocks the iridocorneal angle, commonly caused by pupillary block due to pupil dilation, leading to fluid buildup and increased IOP, potentially resulting in complete vision loss. As a result of an aging population, chronic conditions are increasing in number, necessitating the use of systemic medications to treat them. However, many of these medications may affect the eye, predisposing it to different ocular morbidities. This narrative review will examine the effects of these medications on glaucoma development, specifically focusing on the effects of corticosteroids on OAG through increased aqueous humor resistance in the TM and the effects of sulfonamides, anticholinergics, antidepressants, cholinergics, anticoagulants, and certain supplements on AACG as a result of their sympathomimetic properties and the disruption of the lens-iris structure.

Indexed as

acute angle-closure glaucomadrug-induced glaucomaintraocular pressure (iop)open-angle glaucomasystemic medication

Identifiers

PMID42428212
PMCPMC13346803

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.