Evidence map›Paper›PMID 42428176›Full record

ArticleCureus2026

Renal Resistive Index as a Novel Predictor of Contrast-Induced Acute Kidney Injury in Cirrhosis.

Jesse Jacob Skariah, Rushil Solanki, Jithin John, Akhil N V, Prasanth T S, Antony George, Jijo Varghese, Krishnadas Devadas

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jesse Jacob SkariahGastroenterology and Hepatology, Government Medical College, Thiruvananthapuram, IND.
Rushil SolankiGastroenterology and Hepatology, Ansh Clinic, Ahmedabad, IND.
Jithin JohnGastroenterology and Hepatology, Government Medical College, Thiruvananthapuram, IND.
Akhil N VGastroenterology and Hepatology, Government Medical College, Thiruvananthapuram, IND.
Prasanth T SGastroenterology, Government Medical College, Thiruvananthapuram, IND.
Antony GeorgeGastroenterology and Hepatology, Government Medical College, Thiruvananthapuram, IND.
Jijo VargheseGastroenterology and Hepatology, N.S. Cooperative Hospital, Kollam, IND.
Krishnadas DevadasGastroenterology and Hepatology, Government Medical College, Thiruvananthapuram, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with liver cirrhosis undergo repeated contrast-enhanced imaging procedures. We investigated the risk factors for contrast-induced acute kidney injury (CI-AKI) in cirrhotic patients with normal renal function.

methodsA prospective observational cohort study included 110 consecutive patients with cirrhosis who underwent iodinated contrast (IC)-based imaging procedures. Baseline demographic, clinical, and laboratory data and Renal Resistive Index (RRI) were recorded prior to imaging. All patients were assessed for the development of CI-AKI 48-72 hours after contrast administration.

resultsA total of 34 (30.9%) patients developed CI-AKI after contrast administration. Prior history of acute kidney injury (AKI) was seen in 18 (52.9%) patients who developed CI-AKI and 4 (5.3%) patients who did not develop CI-AKI (p < 0.001). Alcohol-related liver disease was the major etiological factor of cirrhosis in 18 (52.9%) patients with CI-AKI as opposed to 23 (30.3%) patients without CI-AKI (p = 0.047). Baseline estimated glomerular filtration rate (eGFR) and serum creatinine levels were not associated with an increased risk of CI-AKI. Higher values of baseline RRI were seen in patients who developed CI-AKI. On univariate analysis, gender, prior history of AKI, grade III ascites, hepatic encephalopathy, Child-Turcotte-Pugh (CTP) score, Model for End-Stage Liver Disease-Sodium (MELD-Na), and Renal Resistive Index (RRI) were found to be significant risk factors for predicting CI-AKI. On multivariate analysis, Renal Resistive Index (RRI), CTP score, and MELD-Na score were associated with an increased risk of CI-AKI. Preprocedural RRI >0.62, CTP score >10, and MELD-Na >24 had significant predictive value for the occurrence of CI-AKI.

conclusionAdvanced liver cirrhosis was associated with an increased risk of CI-AKI. RRI is an easily available and simple radiologic technique to predict the occurrence of CI-AKI among patients with liver cirrhosis with normal renal function tests.

Indexed as

cirrhosiscomputed tomography (ct) scancontrast-induced acute kidney injury (ci-aki)creatinineimagingiodinated contrast (ic)meld-narenal resistive index (rri)

Identifiers

PMID42428176
PMCPMC13345811

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