Evidence map›Paper›PMID 42427997›Full record

ArticleNational science review2026

Direct ink writing of tantalum: tailorable hierarchical porous scaffold for osteogenesis.

Guangbin Zhao, Bochen Li, Ruiyan Liu, Zhenhua Zhou, Yuxin Gong, Lin Gao, Yating Nie, Xu Chen, Yanlong Wu, Xiaoxi Shao and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in National science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Guangbin ZhaoState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an 710054, China.
Bochen LiState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an 710054, China.
Ruiyan LiuState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, China.
Zhenhua ZhouDepartment of Orthopaedic Oncology, Changzheng Hospital, Naval Military Medical University, Shanghai 200003, China.
Yuxin GongState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an 710054, China.
Lin GaoState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an 710054, China.
Yating NieState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, China.
Xu ChenSchool of Mechatronic Engineering and Automation, Foshan University, Foshan 528000, China.
Yanlong WuSchool of Mechatronic Engineering and Automation, Foshan University, Foshan 528000, China.
Xiaoxi ShaoState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, China.
Yichao GongSchool of Materials Science and Engineering, Xi'an University of Technology, Xi'an 710048, China.
Bo LiState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an 710054, China.ORCID https://orcid.org/0000-0002-7513-0657
Jianru XiaoDepartment of Orthopaedic Oncology, Changzheng Hospital, Naval Military Medical University, Shanghai 200003, China.
Yaxiong LiuSchool of Mechatronic Engineering and Automation, Foshan University, Foshan 528000, China.
Bingheng LuState Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an 710054, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To mitigate the risk of osseointegration failure in bone defect reconstruction, innovative fabrication strategies for developing implants with optimal biocompatibility and enhanced osteogenic capacity are crucial. Hierarchical porous structures formed by the synergistic combination of macropores (∼300-600 μm) and micropores (smaller than 20 μm) can better mimic the structural characteristics of native bone, thereby promoting osteogenesis. In this study, we developed direct ink writing (DIW) technology to fabricate a graded porous tantalum scaffold designed to promote osteogenesis. In the DIW printing process, a rheologically optimized ink and carefully calibrated printing parameters were utilized, enabling stable fabrication of patient-specific scaffold precursors with well-defined macropores. Following a controlled sintering process, the scaffolds exhibited macropores (∼400-500 μm in diameter) and interconnected micropores (∼0.5-23 μm in diameter), allowing tailoring of the mechanical properties and porosity to closely approximate those of native human bone. The well-controlled hierarchical porous structure exhibited excellent biocompatibility and significantly increased osteoinductive performance both

Indexed as

bone implantdirect ink writinghierarchical porous metalosteogenesistantalum

Identifiers

PMID42427997
PMCPMC13348250

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.