Evidence map›Paper›PMID 42427984›Full record

ArticleChemical science2026

Single-carbon insertion enables conversion of cyclopropenes into cyclobutenes: access to oxaspiro[2.3]hexenes.

Maria Chiara Cabua, Iktedar Mahdi, Ernesto Mesto, Emanuela Schingaro, Francesco Secci, Sehrish Sarfaraz, Marco Colella, Philipp Natho, Nadeem S Sheikh, Renzo Luisi

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In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Chiara CabuaDepartment of Pharmacy-Drug Sciences, University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy Renzo.Luisi@uniba.it.ORCID https://orcid.org/0000-0002-3151-9302
Iktedar MahdiDepartment of Pharmacy-Drug Sciences, University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy Renzo.Luisi@uniba.it.
Ernesto MestoDepartment of Earth and Geoenvironmental Sciences, University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy.
Emanuela SchingaroDepartment of Earth and Geoenvironmental Sciences, University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy.
Francesco SecciDipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari S.S. 554, bivio per Sestu Monserrato (Ca) Italy.
Sehrish SarfarazDepartment of Chemistry GGDC Chitti Dheri Mansehra, Higher Education Department KP 21300 Pakistan.
Marco ColellaDepartment of Pharmacy-Drug Sciences, University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy Renzo.Luisi@uniba.it.ORCID https://orcid.org/0000-0001-7673-5335
Philipp NathoDepartment of Pharmacy-Drug Sciences, University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy Renzo.Luisi@uniba.it.
Nadeem S SheikhChemical Sciences, Faculty of Science, Universiti Brunei Darussalam Jalan Tungku Link Gadong BE1410 Brunei Darussalam.ORCID https://orcid.org/0000-0002-0716-7562
Renzo LuisiDepartment of Pharmacy-Drug Sciences, University of Bari Aldo Moro Via E. Orabona 4 70125 Bari Italy Renzo.Luisi@uniba.it.ORCID https://orcid.org/0000-0002-9882-7908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report 1-oxaspiro[2.3]hex-4-enes as a novel strained spiro heterocycle. This motif was accessed

Identifiers

PMID42427984
PMCPMC13348279

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.