ArticleFrontiers in pediatrics2026
Genetic insights into autism spectrum disorder with intellectual disability: a regional population-based study from Northwest China.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the genetic etiology of autism spectrum disorder with Intellectual Disability in the Northwest China. Methods and results: Whole-exome sequencing was conducted on 125 children admitted to Yinchuan First People's Hospital. Variants and associated pathogenic mechanisms were analyzed, as well as correlations between genotypes and clinical phenotypes. Forty-five positive cases were identified from 125 cases, yielding a positive detection rate of 36.0%, with a male-to-female ratio of 2:1. These included 8 cases with copy number variations and 37 cases of single-nucleotide variations/insertions and deletions. Chi-squared tests and False Discovery Rate adjust showed significant differences in gross motor developmental delay and abnormal electroencephalograms between the positive group and part of the negative group ( Conclusion: This study identified several pathogenic genes that have been rarely reported in the context of autism spectrum disorder. Patients with these genetic variants may present with more complex and severe clinical phenotypes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.