ArticleLaryngoscope investigative otolaryngology2026
Utilizing Dynamic Liquid Crystal Elastomer Dressings to Enhance Early Dermal Wound Closure.
Article in Laryngoscope investigative otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
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Abstract
Objective: To evaluate whether a novel body temperature-activated liquid crystal elastomer (LCE) bandage with contraction properties can accelerate wound closure in a porcine model. Methods: Adult pigs underwent creation of thirty-six 8-mm circular full-thickness dermal wounds. LCE strips were assembled into bandages and applied to half of the wounds, while the remaining wounds received conventional dressings within the same animal. Wound size was measured over 14 days and expressed as percent wound area relative to baseline. A total of 144 wounds were analyzed across 4 pigs (LCE group, Results: LCE-treated wounds demonstrated accelerated early reduction in wound area compared with controls (postoperative day [POD] 3: 88.7% vs. 101.5%; POD7: 56.2% vs. 75.0%; POD10: 36.1% vs. 66.7%; all Conclusions: Liquid crystal elastomer materials show promise as a novel approach for enhancing early dermal wound closure. LCE-based dynamic bandages may have future clinical utility as a noninvasive mechanically active wound dressing platform. Level of Evidence: NA.
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