ArticleResearch square2026
A Novel Marker-Based Registration Method for Simultaneous Preclinical PET/MR with a Non-Stationary PET Detector.
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
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Authors and funding
5 authors.
Funding
Abstract
Purpose: To develop a novel, fully automated marker-based method for registering PET images from a small, non-stationary, retrofitted preclinical PET detector to simultaneously acquired MRI images. Methods: We manufactured a nose cone tract with geometric markers from a material visible when imaged with a zero-echo-time MRI sequence. A one-time universal calibration determined the relation between the PET image space and the nose cone tract markers. An experiment-specific calibration was needed to determine the location of the nose cone tract markers in laboratory space, and, hence, in MRI image space. The robustness of the method was evaluated through systematic experiments. Results: Experiments demonstrated successful registration of the two imaging modalities with a spatial registration error below the PET voxel size. Conclusion: The proposed registration approach is a practical method for registering simultaneously acquired PET and MR images with sub-voxel precision when the PET device is non-stationary and the usable space inside the detector is too small for dual-modality fiducial markers.
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Registered trials
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