ArticleResearch square2026
Heterochronic Expression of TFAP2β in Coarctation of the Aorta.
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
Abstract
Coarctation of the aorta (CoA) is an anatomically defined lesion with a surgical solution and no established mechanistic etiology. TFAP2β has demonstrated specificity to ductal smooth muscle cells in CoA. In mammalian models, ductal TFAP2β protein expression declines across the third trimester, with protein undetectable at or near term in mice and rats as well as corroborating mRNA decline in non-human primates. We report robust postnatal TFAP2β protein colocalized to the elastin-poor obstructive shelf in a surgical CoA resection.
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Registered trials
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