Evidence map›Paper›PMID 42427715›Full record

ArticlebioRxiv : the preprint server for biology2026

Generation and MHC class II loading of an endogenous influenza epitope revealed by a T cell receptor-like antibody.

Linlin Yang, Michael J Hogan, Stephen D Carro, Emma J Hedgepeth, Jianqiu Du, Mary E O'Mara, Kathleen S Krauss, Robert Novak, Christabel Ameyaw Baah, Nhu Le and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Linlin YangPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-5602-4157
Michael J HoganDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-6244-2993
Stephen D CarroPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0003-3756-1429
Emma J HedgepethDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA, USA.
Jianqiu DuVaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, USA.ORCID 0009-0001-2626-6590
Mary E O'MaraDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA, USA.
Kathleen S KraussPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-9432-6623
Robert NovakDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA, USA.
Christabel Ameyaw BaahDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA, USA.
Nhu LeDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA, USA.
Chaitali BhadiadraDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA, USA.
Jesper PallesenVaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, PA, USA.ORCID 0000-0002-3270-1587
Laurence C EisenlohrDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA, USA.ORCID 0000-0002-8475-7910

Funding

COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCH75N93019C00051 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2019 to 2025
$105.4M
Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Aaron Robert Goldman · 1985 to 2026
$75.9M
A New Cryo-Transmission Electron Microscope at Thomas Jefferson UniversityS10OD030457 · OD · THOMAS JEFFERSON UNIVERSITY · PI CINGOLANI, GINO · 2022 to 2022
$2.0M
Defining the four major routes of MHC class II antigen processing and presentation with influenza antigensR01AI180250 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI Laurence Crane Eisenlohr · 2024 to 2026
$1.8M
Purchase of a Biacore T200 Surface Plasmon Resonance Label-free Detection SystemS10OD012063 · OD · WISTAR INSTITUTE · PI LIEBERMAN, PAUL M. · 2013 to 2013
$367k
NCI NIH HHS P30 CA010815NIAID NIH HHS P30 AI045008NIAID NIH HHS R01 AI180250NIH HHS 75N93019C00051NIH HHS S10 OD012063NIH HHS S10 OD030457
6 · The paper itself

Abstract

CD4

Identifiers

PMID42427715
PMCPMC13345222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.