Evidence map›Paper›PMID 42427699›Full record

ArticlebioRxiv : the preprint server for biology2026

Novel human monoclonal antibodies with enhanced sensitivity for lipoarabinomannan antigens present in urines of TB patients.

Alok Choudhary, Deendayal Patel, William J Honnen, Afsal Kolloli, Charles Reichman, Kamaljit Kaur, Ruixiang Blake Zheng, Elizabeth Nakabugo, Nasinghe Emmanuel, Lydia Nakiyingi and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alok ChoudharyRutgers Health, New Jersey Medical School, N.J., USA.ORCID 0000-0002-2933-9812
Deendayal PatelRutgers Health, New Jersey Medical School, N.J., USA.ORCID 0000-0003-4483-638X
William J HonnenRutgers Health, New Jersey Medical School, N.J., USA.ORCID 0000-0003-3320-2162
Afsal KolloliRutgers Health, New Jersey Medical School, N.J., USA.ORCID 0000-0002-4840-1685
Charles ReichmanRutgers Health, New Jersey Medical School, N.J., USA.ORCID 0000-0003-3465-3774
Kamaljit KaurRutgers Health, New Jersey Medical School, N.J., USA.
Ruixiang Blake ZhengDepartment of Chemistry, Univeristy of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0001-8200-6534
Elizabeth NakabugoInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-6161-6720
Nasinghe EmmanuelInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Lydia NakiyingiInfectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-7263-3198
Todd LowaryInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.ORCID 0000-0002-8331-8211
Abraham PinterRutgers Health, New Jersey Medical School, N.J., USA.ORCID 0000-0002-3262-3304

Funding

Enhanced POC assay for TB in HIV-infected children based on the ultrasensitive detection of the urinary form of the lipoarabinomannan antigenR01AI152157 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI PINTER, ABRAHAM · 2020 to 2024
$3.9M
Development of a highly-sensitive urine test for tuberculosis (TB) that detects diverse forms of urinary TB lipoarabinomannan (uLAM)R56AI171023 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI PINTER, ABRAHAM · 2022 to 2022
$783k
Bill & Melinda Gates Foundation INV-004048NIAID NIH HHS R01 AI152157NIAID NIH HHS R56 AI171023
6 · The paper itself

Abstract

Lipoarabinomannan (LAM) is a useful biomarker for detection of

Identifiers

PMID42427699
PMCPMC13345352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.