Evidence map›Paper›PMID 42427681›Full record

ArticlebioRxiv : the preprint server for biology2026

Regulatory architecture controlling terminal differentiation of an interoceptive paraneuron in

Hongzhu Ji, Berta Vidal, Elisabeth Conklin, Tergel Enkhtuvshin, Nathan E Schroeder, Oliver Hobert

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Hongzhu JiColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.
Berta VidalColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.
Elisabeth ConklinUniversity of Illinois at Urbana-Champaign, Department of Crop Sciences, Urbana IL 61801.
Tergel EnkhtuvshinColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.
Nathan E SchroederUniversity of Illinois at Urbana-Champaign, Department of Crop Sciences, Urbana IL 61801.
Oliver HobertColumbia University, Department of Biological Sciences, Howard Hughes Medical Institute, New York, NY 10027.ORCID 0000-0002-7634-2854

Funding

Center for C elegans AnatomyR24OD010943 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DAVID H. HALL, Nathan Schroeder · 2012 to 2026
$9.6M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
LIM HOMEOBOX GENE LIM-6 IN MOTOR NEURON DIFFERENTIATIONR01NS039996 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Oliver Hobert · 2001 to 2026
$6.8M
NIH HHS P40 OD010440NIH HHS R24 OD010943NINDS NIH HHS R01 NS039996
6 · The paper itself

Abstract

Interoceptive paraneurons are neuron-like cells located within internal epithelial cell surfaces that sense internal stimuli to evoke specific behavioral or physiological responses. The elucidation of terminal differentiation programs of paraneurons is expected to provide insights into how epithelial cells acquire neuron-like feature during development and possibly also over evolutionary time. We define here transcriptional programs that control the terminal differentiation of an interoceptive paraneuron class in the nematode

Identifiers

PMID42427681
PMCPMC13345242

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.