ArticlebioRxiv : the preprint server for biology2026
Viral infection drives cell-intrinsic re-localization of the
Lakshmi E Batachari, Tyler D Bechtel, Zhouxin Shen, Emily R Troemel
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
4 authors.
Lakshmi E BatachariSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.
Tyler D BechtelSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.
Zhouxin ShenSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.
Emily R TroemelSchool of Biological Sciences, University of California, San Diego, La Jolla, California, United States.ORCID 0000-0003-2422-0473 Funding
UCSD/SDSU IRACDAK12GM068524 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TREJO, JOANN · 2003 to 2025
$24.4MEnhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5MThe Intracellular Pathogen Response Triggers Defense Against Co-evolved PathogensR01GM114139 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2015 to 2026
$3.1MProbing organismal proteostasis through the response to intracellular infectionR01AG052622 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2017 to 2026
$2.7MInnate immunity against viral infection in intestinal epithelial cells of C. elegansR01AI176639 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Emily R Troemel · 2023 to 2026
$1.5MIllumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600kDissecting host-virus interactions in epithelial cellsF31AI176729 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Lakshmi Elaine Batachari · 2024 to 2026
$84kNIAID NIH HHS F31 AI176729NIAID NIH HHS R01 AI176639NIA NIH HHS R01 AG052622NIGMS NIH HHS K12 GM068524NIGMS NIH HHS R01 GM114139NIH HHS P40 OD010440NIH HHS S10 OD026929
6 · The paper itselfAbstract
Detection of viral infection leads to both cell-intrinsic and cell-extrinsic responses. In mammals, cell-intrinsic detection of viral infection leads to cell-extrinsic activation of STAT (Signal Transduction and Activators of Transcription) proteins, a family of transcription factors that promote anti-viral defense. In the nematode
Indexed as
C. elegansinnate immunityintestinal immunitynuclear localization dynamicsOrsay virusRIG-I-like receptorSTAT transcription factorviral infection
Identifiers
PMID42427644
PMCPMC13344970
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