ArticlebioRxiv : the preprint server for biology2026
A Simple, Cost-Effective, High-Throughput Method for Measuring Chromatin Accessibility and Gene Expression in Single Nuclei.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
2 authors.
Funding
Abstract
We describe microfluidic-free, droplet-based methods for single-nucleus epigenomic measurements: Particle-templated Instant Partition single-nucleus assay for transposase-accessible chromatin using sequencing (PIP-ATAC-seq) and its multiomic version (PIP-Multiome-seq). We benchmarked these assays by generating data sets containing thousands of nuclei using cell lines and mouse brains and compared to other established methods. PIP-Multiome and PIP-ATAC are straightforward to implement, affordable, and produce high-quality data, providing useful additions to the single-cell molecular measurement armamentarium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.