Evidence map›Paper›PMID 42427586›Full record

ArticlebioRxiv : the preprint server for biology2026

Host adaptation drives genome evolution and virulence diversification in a bacterial zoonotic pathogen.

Giraud-Gatineau Alexandre, Weke Kenneth, Ouazahrou Rania, Pulido Francisco, Monot Marc, Benaroudj Nadia, Veyrier Frederic, Pětrošová Helena, Picardeau Mathieu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giraud-Gatineau AlexandreInstitut Pasteur, Biology of Spirochetes Unit, Université Paris Cité, F-75015, Paris, France.ORCID 0000-0003-0984-597
Weke KennethUniversity of Victoria, School of Molecular Life Sciences, Victoria, BC, Canada.
Ouazahrou RaniaInstitut Pasteur, Plate-forme Technologique Biomics, Université Paris Cité, F-75015 Paris, France.ORCID 0009-0009-5449-0248
Pulido FranciscoINRS-Centre Armand-Frappier Santé Biotechnologie, Bacterial Symbionts Evolution, Laval, Quebec H7V 1B7, Canada.ORCID 0009-0000-4923-1879
Monot MarcInstitut Pasteur, Plate-forme Technologique Biomics, Université Paris Cité, F-75015 Paris, France.ORCID 0000-0003-0738-7335
Benaroudj NadiaInstitut Pasteur, Biology of Spirochetes Unit, Université Paris Cité, F-75015, Paris, France.ORCID 0000-0002-6475-0041
Veyrier FredericINRS-Centre Armand-Frappier Santé Biotechnologie, Bacterial Symbionts Evolution, Laval, Quebec H7V 1B7, Canada.ORCID 0000-0002-8574-0547
Pětrošová HelenaUniversity of Victoria, School of Molecular Life Sciences, Victoria, BC, Canada.ORCID 0009-0008-9756-7236
Picardeau MathieuInstitut Pasteur, Biology of Spirochetes Unit, Université Paris Cité, F-75015, Paris, France.ORCID 0000-0002-5338-5579

Funding

Virulence and Adaptation to the Host Environment of Pathogenic LeptospiraP01AI168148 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DAVID A HAAKE · 2023 to 2026
$11.8M
NIAID NIH HHS P01 AI168148
6 · The paper itself

Abstract

Understanding how zoonotic pathogens diversify across reservoir hosts remains a central question in evolutionary biology and infectious disease research. Here, we address this challenge using

Identifiers

PMID42427586
PMCPMC13345303

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.