ArticlebioRxiv : the preprint server for biology2026
Bacterial and human exonucleases mediate interkingdom antiviral immunity.
Courtney R Santos, Alyaa El-Guindy, Aaron Embry, Arabella E Martin, Neal M Alto, Don B Gammon, Kevin J Forsberg
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Courtney R SantosDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Alyaa El-GuindyDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Aaron EmbryDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Arabella E MartinDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Neal M AltoDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Don B GammonDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Kevin J ForsbergDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-1545-8925 Funding
Discovery of bacterial defense and phage counter-defense strategiesDP2AI154402 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI FORSBERG, KEVIN J · 2021 to 2025
$2.6MExploiting Pathogen-Encoded Immune Evasion Proteins to Uncover Evolutionarily Conserved Antiviral Host MachineryR35GM137978 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Don Brad Gammon · 2020 to 2026
$2.5MMechanisms of Disease and Translational ScienceT32GM131945 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Thomas Joseph Carroll · 2019 to 2026
$1.7MDefining virulence factor functions using minimal pathogen genomesR01AI191274 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Neal Mathew Alto · 2026 to 2026
$596kNIAID NIH HHS DP2 AI154402NIAID NIH HHS R01 AI191274NIGMS NIH HHS R35 GM137978NIGMS NIH HHS T32 GM131945
6 · The paper itselfAbstract
All kingdoms of life have developed strategies to limit viral infection
Indexed as
EvolutionExonucleasesInnate ImmunityISG20Phage DefenseRNA Viruses
Identifiers
PMID42427507
PMCPMC13344964
What OpenQuestion holds
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