ReviewAdvanced biomedical research2026
An Updated Systematic Review and Meta-Analysis of the Efficacy and Safety of Catheter Ablation in Comparison to Antiarrhythmic Drugs for Managing Atrial Fibrillation.
Review in Advanced biomedical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This meta-analysis compares the efficacy and safety of catheter ablation with antiarrhythmic therapy for atrial fibrillation (AF) in randomized controlled trials (RCTs) We systematically searched PubMed, Web of Science, Google Scholar, Embase, and Cochrane Library for RCTs published in English. Studies comparing catheter ablation (radiofrequency or cryoablation) with antiarrhythmics for rate or rhythm control in adults with AF were included. Data were independently extracted by two investigators. The quality of evidence was assessed using GRADE analysis. 18 RCTs involving 3725 patients were included. The overall risk of bias was adjudicated to be "low." On meta-analysis, catheter ablation significantly increased the likelihood of being free from recurrent atrial arrhythmia, with a 49% reduction rate over a median follow-up of 12 months (RR: 0.51; 95% CI: 0.42-0.63;
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