Evidence map›Paper›PMID 42427219›Full record

ArticleUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2026

Predicting bladder-to-uterine adhesions in patients undergoing hysterectomy using sliding-bladder sign technique with preoperative ultrasound: a diagnostic accuracy study.

J van Keizerswaard, S M Freger, I Mick, A Shishkina, M Marien, R A de Leeuw, J A F Huirne, A A Mosher, M Leonardi

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In one paragraph

Article in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

J van KeizerswaardDepartment of Obstetrics & Gynecology, Amsterdam University Medical Center, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0009-0008-5975-2748
S M FregerDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0001-5534-3965
I MickDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada.
A ShishkinaDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0009-0008-6407-6713
M MarienDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0002-1282-0095
R A de LeeuwDepartment of Obstetrics & Gynecology, Amsterdam University Medical Center, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-9344-7754
J A F HuirneDepartment of Obstetrics & Gynecology, Amsterdam University Medical Center, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-8248-2677
A A MosherDepartment of Obstetrics and Gynecology, West Lincoln Memorial Hospital, Grimsby, ON, Canada.ORCID https://orcid.org/0009-0003-2703-8498
M LeonardiDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0001-5538-6906

Funding

Cansage
6 · The paper itself

Abstract

objectiveThis study aimed to determine the accuracy of the sliding-bladder sign assessed using preoperative transvaginal ultrasound (TVS) for identifying the presence of bladder-to-uterine (BTU) adhesions in patients undergoing hysterectomy.

methodsThis was a prospective diagnostic test-accuracy study conducted at Hamilton Health Sciences, Hamilton, ON, Canada. Patients scheduled for a planned laparascopic hysterectomy for a benign gynecological condition between October 2021 and December 2024 were included and all underwent preoperative TVS examination that included assessment of the sliding-bladder sign. The presence of BTU adhesions was assessed using TVS (index test) and confirmed at hysterectomy (reference standard) by independent assessors who were blinded to the outcome of the other test. The accuracy, specificity, sensitivity, positive and negative predictive values and positive and negative likelihood ratios of the sliding-bladder sign were calculated.

resultsOf 128 included women, 28.1% had BTU adhesions confirmed at hysterectomy. The sliding-bladder sign on preoperative TVS demonstrated an accuracy of 89.1% (95% CI, 82.3-93.9%), with a sensitivity of 69.4% (95% CI, 51.9-83.6%) and a specificity of 96.7% (95% CI, 90.1-99.3%). The positive predictive value was 89.3% (95% CI, 72.8-96.3%), while the negative predictive value was 89.0% (95% CI, 83.2-93.0%). The positive likelihood ratio was 21.3 (95% CI, 6.8-66.2) and the negative likelihood ratio was 0.3 (95% CI, 0.2-0.5).

conclusionsThe sliding-bladder sign assessed using TVS is a non-invasive tool for predicting the presence of BTU adhesions that is reliable when bladder sliding is absent. Incorporating this assessment into preoperative ultrasound examinations may support anatomical anticipation of anterior-compartment adhesions and perioperative preparedness as part of a comprehensive evaluation. © 2026 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

Indexed as

HysterectomyPreoperative CareUrinary BladderUterine DiseasesAdultFemaleHumansMiddle AgedPredictive Value of TestsProspective StudiesSensitivity and SpecificityTissue AdhesionsUltrasonographyUterusbladder‐to‐uterine adhesionspreoperative assessmentsliding bladdertransvaginal ultrasound

Identifiers

PMID42427219
PMCPMC13432980

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.