ArticleJournal of global health2026
The global burden of oesophageal cancer from 1990 to 2023 and projections to 2040: a comprehensive analysis of the Global Burden of Disease Study 2023.
Article in Journal of global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Oesophageal cancer (OC) remains a major global public health challenge. This study aims to analyse the global, regional, and national burden of OC from 1990 to 2023 using the latest data from the Global Burden of Disease (GBD) Study 2023. Methods: Data on EC prevalence, incidence, mortality, and disability-adjusted life years (DALYs) were extracted from GBD 2023. Age-standardised rates (ASRs) were calculated, and temporal trends were assessed using estimated annual percentage changes (EAPCs). Stratified analyses were conducted according to the sociodemographic index (SDI) and risk factor contributions. The disease burden was projected to 2040. Results: In 2023, there were an estimated 1 075 606 prevalent cases of OC globally, with an ASPR of 11.7 per 100 000 population. Although age-standardised rates declined, the absolute number of cases increased by 67% from 1990 to 2023. The disease burden varied substantially across SDI regions and geographical areas, with sub-Saharan Africa and East Asia bearing the heaviest burden. Tobacco use was the leading risk factor contributing to DALYs. The global ASPR is projected to rise to 18.8 per 100 000 by 2040. Conclusions: Despite decreases in age-standardised rates, the absolute burden of OC remains high, with significant variations across regions, countries, and SDI levels. Efforts should be taken in prevention and early diagnosis for OC and to better identify high-risk populations to inform targeted prevention and screening, and ultimately reduce the OC burden in an efficient and cost-effective way.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.