Evidence map›Paper›PMID 42426754›Full record

ArticleBMC musculoskeletal disorders2026

Integrated mechanical and metabolic limb salvage for advanced diabetic Charcot hindfoot collapse with non-traumatic calcaneal fracture: an 8-year follow-up case report.

Koji Nozaka, Hiroshi Aonuma, Kenta Tominaga, Naohisa Miyakoshi

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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Koji NozakaDepartment of Orthopaedic Surgery, Akita University Graduate School of Medicine, Akita, Japan. kk-nozaka@mue.biglobe.ne.jp.ORCID https://orcid.org/0000-0003-0238-8929
Hiroshi AonumaDepartment of Orthopaedic Surgery, Akita University Graduate School of Medicine, Akita, Japan.
Kenta TominagaDepartment of Orthopaedic Surgery, Akita University Graduate School of Medicine, Akita, Japan.
Naohisa MiyakoshiDepartment of Orthopaedic Surgery, Akita University Graduate School of Medicine, Akita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvanced Charcot neuro-osteoarthropathy involving the hindfoot is associated with severe deformity, instability, ulceration, infection, and major lower-limb amputation. Non-traumatic calcaneal fracture associated with diabetic Charcot hindfoot collapse is uncommon and difficult to treat because of neuropathy, impaired bone quality, tendon imbalance, soft tissue compromise, and a high risk of fixation failure. Reports describing long-term functional limb preservation in patients with advanced Charcot hindfoot collapse associated with severe metabolic bone impairment remain limited. CASE PRESENTATION: A 63-year-old Japanese woman with a 36-year history of type 1 diabetes mellitus presented with progressive right hindfoot deformity and ulceration without major trauma. Radiographs and computed tomography demonstrated advanced Charcot hindfoot collapse with a non-traumatic calcaneal fracture classified as Eichenholtz stage III and Brodsky type 3B. Preoperative evaluation demonstrated severe vitamin D deficiency and elevated bone turnover markers. The patient underwent corrective osteotomy of the calcaneus, Achilles tendon Z-lengthening, internal fixation with headless compression screws, autologous iliac bone grafting, and circular external fixation. A staged postoperative unloading protocol was used, followed by gradual protected loading. Sequential metabolic therapy was administered after surgery. Bone union was achieved at approximately 3 months, and the external fixator was removed at 3.5 months. During long-term follow-up, glycaemic control and bone mineral density improved. At 8 years after surgery, the patient remained ambulatory with preserved plantigrade alignment and without recurrent ulceration, infection, fixation failure, or amputation. The American Orthopaedic Foot & Ankle Society ankle-hindfoot score was 94. Interpretation of pain scores was limited by profound diabetic neuropathy.

conclusionsThis case illustrates an integrated multidisciplinary limb-salvage strategy combining mechanical reconstruction, staged postoperative offloading, and metabolic optimisation in a patient with advanced diabetic Charcot hindfoot deformity complicated by severe metabolic bone impairment. The favourable long-term outcome should be interpreted as hypothesis-generating rather than evidence for the efficacy of any individual adjunctive therapy.

Indexed as

Arthropathy, NeurogenicCalcaneusDiabetic FootFractures, BoneLimb SalvageDiabetes Mellitus, Type 1External FixatorsFemaleFollow-Up StudiesHumansMiddle AgedOsteotomyTreatment OutcomeAchilles tendon lengtheningCalcaneal fractureCharcot neuro-osteoarthropathyCircular external fixationHindfootLimb salvageLow-intensity pulsed ultrasoundTeriparatideType 1 diabetes mellitusVitamin D deficiency

Identifiers

PMID42426754
PMCPMC13644240

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.