Evidence map›Paper›PMID 42426747›Full record

ArticleBMC women's health2026

Clinical features and long-term surgical outcomes of ureteral endometriosis with hydroureteronephrosis: a retrospective study.

Xinyue Tang, Zhiyue Gu, Yi Dai, Xiaoyan Li, Shiqing Lyu, Yushi Wu, Chenyu Zhang, Qiutong Li, Hailan Yan, Yuanyuan Li and 2 more

Abstract read
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Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

12 authors.

Xinyue TangNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Zhiyue GuNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Yi DaiNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Xiaoyan LiNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Shiqing LyuNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Yushi WuNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Chenyu ZhangNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Qiutong LiNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Hailan YanNational Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Yuanyuan Li *National Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China.
Jinghua Shi *National Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China. elisa_1984@163.com.
Jinhua Leng *National Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Dongcheng District, Beijing, 100730, China. lengjenny@vip.sina.com.

Funding

the National High Level Hospital Clinical Research Funding 2022-PUMCH-B-085the National Key Clinical Specialty Construction Project Grant No. U114000the National Key R&D Program of China 2022YFC2704000
6 · The paper itself

Abstract

backgroundUreteral endometriosis with hydroureteronephrosis can impair renal function, yet few clear guidelines exist for its surgical treatment. This study aimed to compare the clinicopathological features between patients undergoing ureterolysis with nodule excision versus segmental ureterectomy with anastomosis for ureteral endometriosis with hydroureteronephrosis, and to report the postoperative outcomes.

methodsThis retrospective study included 74 patients with ureteral endometriosis and hydroureteronephrosis who underwent surgery at a tertiary hospital between 2004 and 2024. Clinicopathological characteristics were compared between the ureterolysis and segmental ureterectomy groups using Student's t-test or Mann-Whitney U test for continuous variables, and the χ² test or Fisher's exact test for categorical variables. Variables with P < 0.05 on between-group comparisons were entered into a multivariable logistic regression analysis. Surgical outcomes, including recurrence of hydroureteronephrosis and ureteral complications, were reported.

resultsAmong the 74 patients, 25.7% presented with urinary symptoms. All patients had additional pelvic endometriosis beyond ureteral involvement, including ovarian endometriomas (75.7%) and deep endometriosis at other sites (82.4%). Ureteral endometriosis was classified as extrinsic (82.4%) or intrinsic (17.6%). 54 (73%) patients underwent ureterolysis with nodule excision and 20 (27%) underwent segmental ureterectomy with anastomosis. All 13 intrinsic lesions underwent segmental ureterectomy (P < 0.001). Multivariable analysis revealed that previous endometriosis surgery (OR = 4.413; 95%CI: 1.138-17.108; P = 0.032) and preoperative failed Double-J stenting (OR = 7.833; 95%CI: 1.946-31.522; P = 0.004) were independently associated with the segmental ureterectomy. At a median follow-up of 9 years, the ureterolysis group had 7.4% recurrent hydroureteronephrosis and 1.9% ureteral fistula; the segmental ureterectomy group experienced no recurrent hydroureteronephrosis or ureteral complications.

conclusionsUreteral endometriosis complicated by hydroureteronephrosis often lacks urinary symptoms, with only a minority of lesions classified as intrinsic subtypes, and is almost always accompanied by ovarian endometriomas or deep endometriosis at other pelvic sites. After careful patient selection, 73% of subjects underwent ureterolysis with nodule excision and demonstrated acceptable long-term outcomes. Segmental ureterectomy with anastomosis was reserved for refractory cases, such as patients with intrinsic ureteral lesions, a history of prior endometriosis surgery, or failed preoperative Double-J stenting.

Indexed as

EndometriosisHydronephrosisUreteral DiseasesAdultFemaleHumansRecurrenceRetrospective StudiesTreatment OutcomeUreterHydroureteronephrosisSegmental ureterectomyUreteral endometriosisUreterolysis

Identifiers

PMID42426747
PMCPMC13637158

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