SynthesisBMC pregnancy and childbirth2026
The efficacy of tranexamic acid for the prevention of postpartum hemorrhage among women at high risk of postpartum hemorrhage undergoing cesarean section: a meta-analysis.
Synthesis in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
objectivesThis meta-analysis investigated the extent to which tranexamic acid reduces the risk of postpartum bleeding among pregnant women at high risk of postpartum hemorrhage undergoing cesarean section.
methodsScopus, the Cochrane Library, PubMed, and Web of Science were searched from their establishment to December 4, 2025, to identify randomized controlled trials comparing tranexamic acid with placebo for preventing postpartum hemorrhage in high-risk women undergoing cesarean section. Because of high heterogeneity, we employed a random-effects model (restricted maximum-likelihood) to pool data.
resultsFinally, 12 articles with 1240 high-risk pregnant women were included in this meta-analysis. Compared to placebo, tranexamic acid significantly reduced blood loss after cesarean delivery in high-risk pregnant women (WMD - 435.44 mL, 95% CI (-581.86, -289.01) I
conclusionOur findings suggest that tranexamic acid may effectively reduce bleeding among women with a high risk of postpartum hemorrhage undergoing cesarean section.
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