Evidence map›Paper›PMID 42426444›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Detection and Separation of Circulating Tumor Cells Using Magnetic Fluorescent Nanoparticles.

Shuiling Chen, Yuwei Zhou, Shaobing Zhou, Xia Liu, Jianwen Hou

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuiling ChenInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, China.
Yuwei ZhouInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, China.
Shaobing ZhouInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, China.
Xia LiuSchool of Chemistry, Southwest Jiaotong University, Chengdu, China.
Jianwen HouInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, China. houjianwen@swjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating tumor cells (CTCs) have emerged as indispensable biomarkers in liquid biopsy, offering critical insights for early cancer diagnosis, therapeutic monitoring, and prognostic evaluation. Current immunomagnetic separation methods are prized for their operational simplicity, high specificity, and favorable sensitivity; however, they contend with several significant drawbacks, including the need for complex ligand modification, suboptimal capture efficiency of heterogeneous CTC populations, and the risk of impairing cell viability during subsequent analytical procedures. To address these limitations, we have developed a novel core-shell magnetic fluorescent nanoparticle (FR@Z-pTA NPs) by integrating an Fe

Indexed as

Cell SeparationFluorescent DyesImmunomagnetic SeparationMagnetite NanoparticlesNeoplastic Cells, CirculatingCell Line, TumorCell SurvivalHumansFluorescent DyesMagnetite NanoparticlesBroad-spectrum captureCirculating tumor cellsIn situ labelingMagnetic nanoparticlesStimuli-responsiveness

Identifiers

PMID42426444

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.