Evidence map›Paper›PMID 42426393›Full record

ArticleSurgical endoscopy2026

Effect of improved preoperative activity levels and smoking cessation on ventral hernia repair outcomes.

Emily Flom, Lee Ying, Cassie Hennessy, Andrew Duffy, Randal Zhou

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Emily FlomDepartment of Surgery, Yale School of Medicine, 20 York Street, New Haven, CT, 06511, USA.
Lee YingDepartment of Surgery, Yale School of Medicine, 20 York Street, New Haven, CT, 06511, USA.
Cassie HennessyDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Andrew DuffyDepartment of Surgery, Yale School of Medicine, 20 York Street, New Haven, CT, 06511, USA.
Randal ZhouDepartment of Surgery, Yale School of Medicine, 20 York Street, New Haven, CT, 06511, USA. randal.zhou@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPreoperative patient factors, including baseline physical activity level and smoking status, play an important role in surgical outcomes. This study aims to evaluate whether improved preoperative activity level and smoking cessation decrease surgical complications and improve outcomes for high-risk patients after ventral hernia repair.

methodsUtilizing the Abdominal Core Health Quality Collaborative, a retrospective cohort analysis was conducted. Adult patients undergoing ventral hernia repair who participated in smoking cessation or preoperative exercise were included. Multi-variate logistic regression analyses were used to assess how preoperative exercise and smoking cessation affected primary outcomes including length of stay, 30-day readmission, surgical site infection (SSI), surgical site occurrences (SSO), and surgical site occurrence requiring procedural intervention (SSOPI).

resultsAmong 17,819 patients, in patients with ASA class 2 or higher, any level preoperative exercise regimens improved outcomes. For ASA 2 patients, sporadic and intense exercises were associated with reduced odds of 30-day readmission. Among ASA 3 patients, moderate and intense exercise significantly reduced the risk of SSI. Increasing exercise intensity also demonstrated a trend toward reduced SSO and SSOPI. Smoking cessation within one year prior to surgery was not associated with significant differences in postoperative outcomes compared with active smokers.

conclusionPreoperative exercise improved outcomes after ventral hernia repair, particularly among higher-risk patients (ASA class 2 and above). Specifically, preoperative exercise decreased odds of 30-day readmission, surgical site infections, and surgical site occurrences. These findings suggest that structured preoperative exercise programs may represent an effective, modifiable strategy to improve outcomes in patients undergoing ventral hernia repair. Further research is needed to identify which patient populations derive the greatest benefit from targeted exercise and smoking cessation interventions.

Indexed as

Hernia, VentralHerniorrhaphyPreoperative CarePreoperative ExerciseSmoking CessationAdultAgedFemaleHumansLength of StayMaleMiddle AgedPatient ReadmissionPostoperative ComplicationsRetrospective StudiesSurgical Wound InfectionExercisePrehabilitationSmokingVentral hernia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.