Evidence map›Paper›PMID 42426026›Full record

ArticleNature communications2026

Assembly of Silphium interspecific hybrid genomes opens the genus to phylogenomics, ecogenomics, and molecular breeding.

Renan S Souza, Josh P Clevenger, Jerry Jenkins, Walid Korani, Jeremy Schmutz, Jane Grimwood, Christopher Plott, Yaniv Brandvain, Kathryn Turner, Allison J Miller and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Renan S SouzaHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
Josh P ClevengerHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.ORCID http://orcid.org/0000-0002-9830-9481
Jerry JenkinsHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.ORCID http://orcid.org/0000-0002-7943-3997
Walid KoraniVeil Genomics, Huntsville, AL, USA.ORCID http://orcid.org/0000-0001-5372-2240
Jeremy SchmutzHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.ORCID http://orcid.org/0000-0001-8062-9172
Jane GrimwoodHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.ORCID http://orcid.org/0000-0002-8356-8325
Christopher PlottHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.ORCID http://orcid.org/0000-0002-0109-5174
Yaniv BrandvainUniversity of Minnesota, Minneapolis, MN, USA.
Kathryn TurnerThe Land Institute, Salina, KS, USA.ORCID http://orcid.org/0000-0003-0835-6506
Allison J MillerThe Donald Danforth Plant Science Center, Saint Louis, MO, USA.
Brent S HulkeUSDA-Agricultural Research Service, Edward T Schafer Agricultural Research Center, Fargo, ND, USA.ORCID http://orcid.org/0000-0001-5380-0827
Louis F NastasiDepartment of Entomology, University of Nebraska-Lincoln, Lincoln, NE, USA.ORCID http://orcid.org/0000-0001-7825-480X
Ebony G MurrellSavanna Institute, Madison, WI, USA.
Lori H HandleyHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.ORCID http://orcid.org/0000-0002-9968-6051
Jenell WebberHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
Lori Beth BostonHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
Stella WoeltjenThe Donald Danforth Plant Science Center, Saint Louis, MO, USA.
Matthew J RubinSaint Louis University, Saint Louis, MO, USA.
Betsy TranaThe Land Institute, Salina, KS, USA.
Erin HowardThe University of Georgia, Athens, GA, USA.
Ashlyn BazzelClemson University, Clemson, SC, USA.ORCID http://orcid.org/0009-0002-8391-9372
Alex HarkessHudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.ORCID http://orcid.org/0000-0002-2035-0871
David L Van TasselThe Land Institute, Salina, KS, USA. vantassel@landinstitute.org.ORCID http://orcid.org/0000-0003-0844-3976

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wild perennial plants can be domesticated to make agriculture more diverse and resilient, but many have large genomes that have been recalcitrant to analysis. Here, we report phased genome assemblies for Silphium integrifolium Michx. and S. perfoliatum L., two species native to North America under domestication, and demonstrate the utility of trio-binning for genome assembly using an interspecific hybrid. These genomes have chromosomes reaching 1.8 Gb and a helical structure preserved during interphase with a loop circumference of 43 Mb. A genome-informed low coverage and target sequencing strategy enables the refinement of the genus phylogeny, reveals the spatial distribution and structure of natural populations, and identifies 81 loci associated with environmental and domestication traits. Variants in a MATE transporter, α/β hydrolase, and ortholog of Arabidopsis ACT Domain Repeat (ACR4) protein explain significant variance in floral architecture. These advances in genome assembly and genotyping could expand the range of candidates for de novo crop domestication.

Indexed as

DNA ShufflingGenome, PlantPhylogenyDomesticationGenomicsHybridization, Genetic

Identifiers

PMID42426026
PMCPMC13482097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.