Evidence map›Paper›PMID 42424448›Full record

ArticleScience (New York, N.Y.)2026

Adaptation across an extreme elevational gradient in Andean leaf-eared mice, the world's highest-dwelling mammal.

Schuyler Liphardt, Naim M Bautista, Marcial Quiroga-Carmona, Nathanael D Herrera, L Moritz Blumer, Juan C Opazo, Federico G Hoffmann, Ranim Saleem, Derek A Somo, Francisco Del Basto Llancaqueo and 12 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Schuyler Liphardt *Division of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.ORCID 0000-0001-8370-8722
Naim M Bautista *School of Biological Sciences, University of Nebraska, Lincoln, NE, USA.ORCID 0000-0003-0634-0842
Marcial Quiroga-CarmonaSchool of Biological Sciences, University of Nebraska, Lincoln, NE, USA.ORCID 0000-0002-2321-7777
Nathanael D HerreraDivision of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.
L Moritz BlumerDivision of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.ORCID 0000-0002-5775-1767
Juan C OpazoFacultad de Medicina, Universidad San Sebastián, Valdivia, Chile.ORCID 0000-0001-7938-4083
Federico G HoffmannDepartment of Biochemistry, Nutrition, and Health Promotion, Mississippi State University, Starkville, MS, USA.ORCID 0000-0001-5056-4929
Ranim SaleemDepartment of Biology, McMaster University, Hamilton, ON, Canada.ORCID 0009-0000-3057-5882
Derek A SomoDepartment of Biology, McMaster University, Hamilton, ON, Canada.
Francisco Del Basto LlancaqueoDepartamento de Biología, Facultad de Ciencias Ecologícas, Universidad de Chile, Santiago, Chile.ORCID 0009-0008-8525-1891
Timothy J ThurmanDivision of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.ORCID 0000-0002-9602-6226
Timothy B WheelerDivision of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.ORCID 0000-0003-0668-8662
Daniel E ShawDivision of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.ORCID 0000-0001-8838-304X
Hunter K WaltDepartment of Biochemistry, Nutrition, and Health Promotion, Mississippi State University, Starkville, MS, USA.ORCID 0009-0008-4927-0489
Till S HarterDepartment of Biology, McMaster University, Hamilton, ON, Canada.ORCID 0000-0003-1712-1370
Grant B McClellandDepartment of Biology, McMaster University, Hamilton, ON, Canada.ORCID 0000-0003-1500-9983
Graham R ScottDepartment of Biology, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-4225-7475
Pablo SabatDepartamento de Biología, Facultad de Ciencias Ecologícas, Universidad de Chile, Santiago, Chile.ORCID 0000-0002-6609-9969
Zachary A ChevironDivision of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.ORCID 0009-0006-2089-5579
Guillermo D'ElíaInstituto de Ciencias Ambientales y Evolutivas, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.ORCID 0000-0001-7173-2709
Jeffrey M GoodDivision of Biological and Biomedical Sciences, University of Montana, Missoula, MT, USA.ORCID 0000-0003-0707-5374
Jay F StorzSchool of Biological Sciences, University of Nebraska, Lincoln, NE, USA.ORCID 0000-0001-5448-7924

Funding

Genomic and physiological mechanisms of hypoxia adaptation in high-altitude miceR01HL159061 · NHLBI · UNIVERSITY OF NEBRASKA LINCOLN · PI STORZ, JAY · 2022 to 2025
$1.9M
NHLBI NIH HHS R01 HL159061
6 · The paper itself

Abstract

Andean leaf-eared mice (

Indexed as

AcclimatizationAdaptation, PhysiologicalAltitudeSigmodontinaeAnimalsEcosystemHypoxiaMitochondria, MuscleMuscle, SkeletalSelection, GeneticThermogenesis

Identifiers

PMID42424448
PMCPMC13595044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.