Evidence map›Paper›PMID 42424419›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

A phase oscillator model of cell cycles reveals nuclear density control in a branched fungal network.

Grace A McLaughlin, Benjamin M Stormo, Ameya P Jalihal, Taylor L Pompan, Madhav Mani, Timothy C Elston, Amy S Gladfelter

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Grace A McLaughlinDepartment of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Benjamin M StormoDepartment of Cell Biology, Duke University, Durham, NC 27705.ORCID 0000-0002-6861-8451
Ameya P JalihalDepartment of Cell Biology, Duke University, Durham, NC 27705.
Taylor L PompanDepartment of Cell Biology, Duke University, Durham, NC 27705.ORCID 0009-0003-1351-5767
Madhav ManiDepartment of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, IL 60208.
Timothy C ElstonDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-4601-2117
Amy S GladfelterDepartment of Cell Biology, Duke University, Durham, NC 27705.ORCID 0000-0002-2490-6945

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
Cytoplasmic Organization by phase transitionsR01GM081506 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GLADFELTER, AMY S · 2010 to 2023
$4.0M
Mathematical modeling of cellular signaling systemsR35GM127145 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Timothy C Elston · 2018 to 2026
$3.9M
Organization of Syncytial CellsR35GM156800 · NIGMS · DUKE UNIVERSITY · PI Amy S Gladfelter · 2025 to 2026
$1.1M
Gene Expression Variability and Nuclear Territory Autonomy in SyncytiaF32GM147989 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JALIHAL, AMEYA PRANAV · 2022 to 2023
$137k
NIEHS NIH HHS P30 ES010126NIGMS NIH HHS F32 GM147989NIGMS NIH HHS R01 GM081506NIGMS NIH HHS R35 GM127145NIGMS NIH HHS R35 GM156800NIH HHS GM R35 GM118096NIH HHS NIGMS 1F32GM147989NIH HHS R35GM127145
6 · The paper itself

Abstract

Maintaining an appropriate nuclear-to-cytoplasmic ratio is essential across cell types for physiological function, and mechanisms of size control have been extensively studied in mononucleate cells. Much less is known about how comparable control is achieved in cells where many nuclei share a common cytoplasm, which are seen in many contexts including muscle, placenta, and filamentous fungi. The filamentous fungus

Indexed as

Cell CycleCell NucleusEremotheciumModels, BiologicalCytoplasmcell size controlfungal syncytiaoscillator modeling

Identifiers

PMID42424419
PMCPMC13353206

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.