Evidence map›Paper›PMID 42424357›Full record

ArticlePloS one2026

Serological evidence of SARS-CoV-2 exposure in marine mammals in the United States between 2020 and 2025.

Idrissa Nonmon Sanogo, Wendy B Puryear, Alexa F Simulynas, Robert DiGiovanni, Caroline E Goertz, Natalie Hunter, Kathy Burek Huntington, Natalie Rouse, Rosemary E Seton, Nicole E Hunter and 29 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors.

Idrissa Nonmon SanogoDepartment of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, United States of America.ORCID https://orcid.org/0000-0003-1372-7818
Wendy B PuryearDepartment of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, United States of America.
Alexa F SimulynasDepartment of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, United States of America.ORCID https://orcid.org/0000-0003-4474-2076
Robert DiGiovanniAtlantic Marine Conservation Society, Hampton Bays, New York, United States of America.
Caroline E GoertzAlaska SeaLife Center, Seward, Alaska, United States of America.
Natalie HunterAlaska SeaLife Center, Seward, Alaska, United States of America.ORCID https://orcid.org/0009-0009-6187-3319
Kathy Burek HuntingtonAlaska Veterinary Pathology Services, Eagle River, Alaska, United States of America.
Natalie RouseAlaska Veterinary Pathology Services, Eagle River, Alaska, United States of America.ORCID https://orcid.org/0009-0003-2802-9841
Rosemary E SetonAllied Whale, College of the Atlantic, Bar Harbor, Maine, United States of America.
Nicole E HunterInternational Fund for Animal Welfare, Yarmouth Port, Massachusetts, United States of America.
Kim SchulamMarine Mammal Alliance Nantucket, Nantucket, Massachusetts, United States of America.
Stephen J St PierreMarine Mammal Alliance Nantucket, Nantucket, Massachusetts, United States of America.
Lynda DoughtyMarine Mammals of Maine, Brunswick, Maine, United States of America.
Jay PagelMarine Mammal Stranding Center, Brigantine, New Jersey, United States of America.
Allison D TuttleMystic Aquarium, Mystic, Connecticut, United States of America.
Sarah CallanMystic Aquarium, Mystic, Connecticut, United States of America.
Marina A Piscitelli-DoshkovNorth Carolina Aquariums Jennette's Pier, Nags Head, North Carolina, United States of America.ORCID https://orcid.org/0000-0001-7931-0068
Lisa BeckerNational Marine Life Center, Buzzards Bay, Massachusetts, United States of America.
Brian FadelyMarine Mammal Laboratory, Alaska Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0002-9172-1887
Sarah M ChinnMarine Mammal Laboratory, Alaska Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0001-9155-5359
Anthony J OrrMarine Mammal Laboratory, Alaska Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America.
Heather ZielMarine Mammal Laboratory, Alaska Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America.
Josh LondonMarine Mammal Laboratory, Alaska Fisheries Science Center, National Marine Fisheries Service, NOAA, Seattle, Washington, United States of America.
Jessica L HugginsCascadia Research Collective, Olympia, Washington, United States of America.
Deborah FauquierNational Oceanic and Atmospheric Administration, National Marine Fisheries Service, Office of Protected Resources, Silver Spring, Maryland, United States of America.
Sarah WilkinNational Oceanic and Atmospheric Administration, National Marine Fisheries Service, Office of Protected Resources, Silver Spring, Maryland, United States of America.ORCID https://orcid.org/0000-0002-3103-1745
Ainsley SmithNational Oceanic and Atmospheric Administration Fisheries, Gloucester, Massachusetts, United States of America.
Margot MaddenNational Aquarium, Baltimore, Maryland, United States of America.
Maxine A MontelloNew York Marine Rescue Center, Riverhead, New York, United States of America.ORCID https://orcid.org/0009-0007-6657-4559
Alissa C DemingPacific Marine Mammal Center, Laguna Beach, California, United States of America.
Michelle R RivardSR3 (SeaLife Response, Rehabilitation, and Research), Des Moines, Washington, United States of America.
Ashley StokesSeacoast Science Center, Rye, New Hampshire, United States of America.
Lauren McDowellSeacoast Science Center, Rye, New Hampshire, United States of America.
Joanna DanielVirginia Aquarium and Marine Science Center Stranding Response Program, Virginia Beach, Virginia, United States of America.
Dyanna LambournWashington Department of Fish and Wildlife, Wildlife Program, Science Division, Olympia, Washington, United States of America.
Suzanne ThurmanMarine Education, Research and Rehabilitation Institute, Lewes, Delaware, United States of America.
Michelle BarbieriPacific Islands Fisheries Science Center, National Marine Fisheries Service, NOAA, Honolulu, Hawaii, United States of America.
Claudia CedilloPacific Islands Fisheries Science Center, National Marine Fisheries Service, NOAA, Honolulu, Hawaii, United States of America.
Jonathan A RunstadlerDepartment of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, United States of America.

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00014 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GARCIA-SASTRE, ADOLFO · 2021 to 2025
$62.6M
Resources and workforce development for the New England Regional Biosafety LaboratoryUC7AI180310 · NIAID · TUFTS UNIVERSITY BOSTON · PI Cheryl A London, Sam R Telford · 2023 to 2026
$11.8M
NIAID NIH HHS UC7 AI180310NIH HHS 75N93021C00014NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

Natural infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been documented in over 60 animal species, some distantly related. Several marine mammals have been predicted as highly susceptible to SARS-CoV-2 infection based on the homology of their ACE2 receptors to those of humans. To assess potential exposure of marine mammals to SARS-CoV-2, we conducted an opportunistic survey from 2020 to 2025 and tested 1,808 swabs and 378 serum samples from 21 marine mammal species in the United States. All the swabs tested by RT-qPCR were negative, indicating the absence of active infection. A low level of SARS-CoV-2 neutralizing antibodies was detected in three pinniped species, including Phoca vitulina (harbor seal, 13.6%, 95% CI: 5.2-27.4%), Zalophus californianus (California sea lion, 7%, 95% CI: 1.9-17.0%), and Halichoerus grypus (grey seal, 3.7%, 95% CI: 0.5-12.7%). These findings represent the first serological evidence of SARS-CoV-2 exposure in marine mammals in the United States, highlighting the need for continued monitoring of these populations and further research on SARS-CoV-2 transmission dynamics in wildlife.

Indexed as

Aquatic OrganismsCOVID-19SARS-CoV-2AnimalsAntibodies, NeutralizingAntibodies, ViralCaniformiaHumansMammalsPhocaSea LionsSeroepidemiologic StudiesUnited StatesAntibodies, NeutralizingAntibodies, Viral

Identifiers

PMID42424357
PMCPMC13349194

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.