ArticleMMWR. Morbidity and mortality weekly report2026
Acute Flaccid Myelitis Surveillance - United States, January 2020-December 2025.
Article in MMWR. Morbidity and mortality weekly report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical Characteristics of Enterovirus D68 Respiratory Disease in Colorado Children Over a Decade: 2014-2025.The Pediatric infectious disease journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute flaccid myelitis (AFM) is a rare but serious neurologic condition that causes paralysis and primarily affects children. Clinically and radiologically, AFM is indistinguishable from the acute flaccid paralysis of poliomyelitis caused by poliovirus. Nationwide surveillance for AFM has been conducted in the United States since 2014, when an increase in AFM was first recognized. Laboratory testing and epidemiologic and clinical data collected through surveillance suggest that enteroviruses, particularly enterovirus D68 (EV-D68), are a common cause of AFM. EV-D68 circulation was associated with biennial peaks in AFM cases in the United States in 2014, 2016, and 2018. This report provides an update to nationwide surveillance of confirmed AFM cases during January 2020-December 2025. During this period, the number of confirmed AFM cases reported to CDC remained low (17-48 cases per year) compared with 2014, 2016, and 2018 (120-238 cases per year). Despite ongoing seasonal enterovirus circulation, including increases in EV-D68-associated respiratory illnesses identified from sentinel surveillance sites in 2022, 2024, and 2025, concurrent increases in AFM cases in nationwide surveillance data were not observed; EV-D68 was detected in one AFM patient specimen received by CDC during this period. A majority (approximately 75%) of confirmed cases of AFM occurred in persons who were reported to be up to date with polio vaccination; approximately one half had stool specimens collected and tested. In 2022, a polio case in an unvaccinated person was identified by testing stool specimens collected through AFM surveillance. Clinicians should ensure that stool samples are collected from patients with acute onset of flaccid weakness or paralysis and report all cases to their local health department.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.