ArticleChemistry & biodiversity2026
Antibiofilm, Antimicrobial, and Anti-inflammatory Potential of Rubus chamaemorus Rhizome, Leaf, and Fruit Extracts.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The global rise of antimicrobial resistance is concomitant with an increasing prevalence of chronic wound infections. Medicinal plants are a promising source of novel therapeutic agents. Rubus chamaemorus, a plant native to Northern Europe traditionally used for wound healing, is one of them. Dried, powdered rhizomes, leaves, and fruits of R. chamaemorus were extracted with dichloromethane, methanol, and water. The extracts were screened for antibacterial and antifungal activity. Main compounds were identified using liquid chromatography-mass spectrometry (LC-MS). Biofilm inhibition was assessed using multidrug-resistant Escherichia coli. Cytotoxicity against HaCaT cells, inhibition of 5-lipoxygenase (5-LOX) product formation, chelating, and antioxidant properties were determined. While the rhizome and fruit extracts demonstrated no relevant biological activities, the methanolic leaf extract exhibited a low minimal biofilm inhibitory concentration (MBIC = 30 µg/mL) and a potent 5-LOX inhibition (IC
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