ArticleChemistry & biodiversity2026
Comparative Evaluation of the Cytotoxic Effect of Dysphania ambrosioides Extracts Against Human Breast and Cervical Cancer Cells.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Dysphania ambrosioides, a prominent medicinal plant, exhibits diverse biological properties with emerging potential in cancer research. Despite its therapeutic promise, the relationship between phytochemical composition and biological activities remains insufficiently explored, particularly regarding geographical variation. This study investigates the correlation between the phytochemical profiles of D. ambrosioides extracts from Colombia (DA-Col) and Brazil (DA-Bra) and their cytotoxic activity against HeLa, SiHa, and MCF-7 cancer cell lines. Qualitative chemical profiling revealed distinct presence-and-absence patterns of specific secondary metabolites between the two geographical sources. These geographically driven variations in the phytochemical profile directly influenced the observed biological activity, with the extracts exhibiting differential cytotoxicity profiles. Specifically, Colombian extract DA-Col-1 showed significant activity against HeLa cells (IC
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