ArticleJapanese journal of ophthalmology2026
Acute retinal necrosis: an assessment of vitreous and retinal detachment.
Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo examine the relationship between posterior vitreous changes and retinal detachment (RD) associated with acute retinal necrosis (ARN). STUDY
designRetrospective, consecutive case study.
methodsThis study evaluated the clinical findings for 32 eyes of 29 patients (12 women, 17 men) diagnosed with ARN, with the posterior vitreous condition monitored by swept-source optical coherence tomography (SS-OCT). The causative virus, incidence of RD, and relationship between the development of RD and final visual acuity were investigated. Patients were checked for posterior vitreous detachment (PVD) from the initial visit to the last SS-OCT observation.
resultsVaricella-zoster virus caused 67% of the ARN cases, with RD developing in 66% of the cases, and proliferative vitreoretinopathy (PVR) in 90% at onset or at recurrence. Silicone oil could not be removed in 38% of the cases with RD. Final best-corrected visual acuity was significantly worse in the RD (+) group than in the RD (-) group (median logMAR 1.02 vs. 0.16, p = 0.04). PVD occurred in 20 of 21 eyes without PVD at the initial examination, with 18 of these 20 eyes developing RD (90%). PVD occurred at an average of 45.8 ± 32.1 days after the initial examination, with 85% of the cases developing PVD within 3 months.
conclusionsThe visual prognosis of ARN complicated by RD is poor. PVD is involved in the development of RD and is often associated with PVR, which itself is refractory.
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