Evidence map›Paper›PMID 42423777›Full record

Observational studySurgical endoscopy2026

Conversion to open surgery during robotic pancreatoduodenectomy in surgical high-risk groups: patterns, risk factors, and outcomes in elderly and/or obese patients.

Tiziana Marchese, Valentina Valle, Benedetto Ielpo, Annalisa Comandatore, Gregorio Di Franco, Roberto Salvia, Sharona Ross, John B Martinie, Curtis J Wray, Marcello G Spampinato and 4 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tiziana MarcheseGeneral and HPB Surgery Department, Lecce, Italy.
Valentina ValleDivision of Minimally Invasive, General & Robotic Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Benedetto IelpoHPB Unit, Hospital Del Mar, Pompeu Fabra University, Passeig Maritim 25, 08034, Barcelona, Spain. ielpo.b@gmail.com.ORCID http://orcid.org/0000-0003-3129-3208
Annalisa ComandatoreGeneral Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Gregorio Di FrancoGeneral Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Roberto SalviaDepartment of General and Pancreatic Surgery, The Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Sharona RossHepatopancreatobiliary Surgery, AdventHealth Tampa, Digestive Health Institute, Tampa, FL, USA.
John B MartinieDivision of HPB Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Curtis J WrayDepartment of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Marcello G SpampinatoGeneral and HPB Surgery Department, Lecce, Italy.
Paraskevas PakataridisFaculty of Medicine, Sofia University "St. Kliment Ohridski", Sofia, Bulgaria.
Pier Cristoforo GiulianottiDivision of Minimally Invasive, General & Robotic Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Luca MorelliGeneral Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
PANFRAIL Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConversion to laparotomy during robotic pancreatoduodenectomy (RPD) carries important clinical implications, yet its incidence, predictors, and consequences in elderly and/or obese patients remain poorly characterized. This study aimed to define the conversion rate, identify preoperative predictors, and assess the impact of conversion on postoperative outcomes in elderly and/or obese surgically high-risk patients undergoing attempted RPD.

methodsA retrospective analysis was performed using a multi-institutional database. Patients were included if they underwent attempted RPD and met at least one high-risk criterion: age ≥ 80 years and/or BMI ≥ 30 kg/m

resultsAmong 311 patients, 36 (11.6%) required conversion to laparotomy. The most common recorded reason was strategic surgeon decision (n = 18, 50.0%), followed by vascular involvement (n = 10, 27.8%), intraoperative complications, and patient instability. On multivariable analysis, independent predictors of conversion were preoperative biliary drainage (OR 7.36; p = 0.021) and vascular involvement (OR 22.22; p = 0.027), while male sex was protective (OR 0.22; p = 0.032). Robotic experience > 20 cases was associated with reduced conversion risk in an adjusted model (aOR 0.17; p = 0.027). Conversion was associated with longer hospital stay, higher 30-day and 90-day mortality, and increased postoperative complications. Clinically relevant postoperative pancreatic fistula rates were similar between groups overall.

conclusionsIn elderly and/or obese surgically high-risk patients selected for attempted RPD, conversion occurred in approximately one in nine cases and was associated with worse short-term outcomes. These findings support careful patient selection, recognition of vascular complexity, transparent counseling, and a low threshold for strategic conversion in expert robotic pancreatic programs. Conversion should not be interpreted uniformly as operative failure, because its implications differ according to mechanism and timing.

Indexed as

Conversion to Open SurgeryObesityPancreaticoduodenectomyRobotic Surgical ProceduresAgedAged, 80 and overAge FactorsFemaleHumansMalePostoperative ComplicationsRetrospective StudiesRisk FactorsTreatment OutcomeConversionElderlyHigh-risk patientsObesityOctogenariansRobotic pancreatoduodenectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.