Evidence map›Paper›PMID 42423762›Full record

Trial reportExperimental brain research2026

Load-dependent dissociation between H-reflex amplitude and background EMG activity during oscillatory loading: implications for the bone myoregulation reflex.

Ismet Alkim Ozkan, Fuat Orhun Alayoglu, Eser Kalaoglu, Nida Dogan, Nilgün Yildiz, Muhammed Yurtseven, Kadriye Ones, Ilhan Karacan, Kemal Sıtkı Türker

Abstract readClinical Trial
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In one paragraph

Trial report in Experimental brain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ismet Alkim OzkanDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Sivas Cumhuriyet University, Sivas, Turkey.ORCID http://orcid.org/0000-0001-9202-0065
Fuat Orhun Alayogluİstanbul Physical Therapy Rehabilitation Training and Research Hospital, Adnan Kahveci Blv. No: 145, Bahçelievler, 34186, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-4090-7235
Eser Kalaogluİstanbul Physical Therapy Rehabilitation Training and Research Hospital, Adnan Kahveci Blv. No: 145, Bahçelievler, 34186, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8959-6522
Nida Doganİstanbul Physical Therapy Rehabilitation Training and Research Hospital, Adnan Kahveci Blv. No: 145, Bahçelievler, 34186, Istanbul, Turkey.ORCID http://orcid.org/0009-0002-0696-6394
Nilgün YildizDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul Gelisim University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-7632-9927
Muhammed YurtsevenDepartment of Physiotherapy, Vocational College of Health Services, Istanbul Gelisim University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-7043-7855
Kadriye Onesİstanbul Physical Therapy Rehabilitation Training and Research Hospital, Adnan Kahveci Blv. No: 145, Bahçelievler, 34186, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-9438-4428
Ilhan Karacanİstanbul Physical Therapy Rehabilitation Training and Research Hospital, Adnan Kahveci Blv. No: 145, Bahçelievler, 34186, Istanbul, Turkey. mdkaracanilhan@gmail.com.ORCID http://orcid.org/0000-0002-7462-1358
Kemal Sıtkı TürkerPhysiology Department, Faculty of Dentistry, Istanbul Gelisim University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-9962-075X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Under static postural loading and graded contractions, H-reflex amplitude may be reduced despite increased background EMG activity (BGA), indicating a dissociation between H-reflex amplitude and motor output. Whether oscillatory mechanical loading, such as whole-body vibration (WBV), induces a similar dissociation remains unclear. The bone myoregulation reflex (BMR) is a load-dependent response to oscillatory stimuli. This study investigated whether WBV produces a dissociation between H-reflex excitability and motor output, evaluating the BMR's potential contribution to this dissociation. Fifteen healthy volunteers were assessed during quiet standing under varied postural (single/double-leg) and platform displacement (zero/1.1/2.2 mm) conditions. Soleus H-reflex amplitude (H/Mmax) and normalized BGA were derived from the recorded EMG signals. The reflex evoked during WBV was identified as the BMR. To quantify BMR activity, the rectified EMG signal was integrated over the 8-s vibration period, representing the cumulative motor output induced by the mechanical stimuli. BMR latency was sensitive to postural load distribution. Increasing oscillatory loading magnitude produced a marked reduction in the H/Mmax ratio (p < 0.001, η

Indexed as

H-ReflexMuscle, SkeletalPostural BalanceWeight-BearingAdultElectromyographyFemaleHumansMaleVibrationYoung AdultMuscle spindlePostural controlTonic vibration reflexVibration paradoxWhole-body vibration

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.