ArticleBrain and behavior2026
Altered Sensory Processing in Restless Legs Syndrome: Associations With Disease Severity.
Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Altered Sensory Processing in Restless Legs Syndrome: Associations With Disease Severity.Brain and behavior · 2026Article
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2 authors.
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Abstract
objectiveRestless legs syndrome (RLS) is increasingly recognized as a complex sensory-motor disorder. While its motor symptoms are well-characterized, the broader sensory processing patterns and their clinical implications remain under-explored. This study aimed to evaluate altered sensory processing in RLS patients and investigate its relationship with disease severity and duration.
methodsThis cross-sectional study included 81 RLS patients diagnosed according to IRLSSG criteria. Diagnostic accuracy was verified through clinical records, laboratory data, and prior electromyography reports. Sensory processing was assessed using the Adolescent/Adult Sensory Profile (AASP), and RLS severity was measured with the International Restless Legs Syndrome Rating Scale (IRLS).
resultsRLS patients exhibited a distinct sensory processing profile characterized by significantly higher scores in sensory sensitivity, sensory avoidance, and low registration, and lower scores in sensory seeking compared to normative data. Sensory avoidance was significantly associated with both disease severity (r = 0.22) and disease duration (r = 0.23). Females showed higher low registration scores.
conclusionThe findings suggest that altered sensory processing is a fundamental aspect of the RLS clinical phenotype. The correlation between sensory avoidance and disease severity indicates that a sensory-based perspective may provide valuable clinical insights. Recognizing RLS as a multifaceted sensory-motor syndrome may guide clinicians toward more comprehensive evaluation and personalized management strategies.
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