ArticleJournal of nutrition and metabolism2026
Phase Angle Shows a Negative Correlation With Serum GDF-15 Concentrations in Hospitalized Patients With Cardiovascular Disease.
Article in Journal of nutrition and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Phase Angle Shows a Negative Correlation With Serum GDF-15 Concentrations in Hospitalized Patients With Cardiovascular Disease.Journal of nutrition and metabolism · 2026Article
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Growth differentiation factor (GDF)-15 is associated with various conditions such as cardiovascular disease, inflammation, and chronic kidney disease. Phase angle (PhA) reflects cellular health and nutritional status. However, the relationship between serum GDF-15 concentrations and PhA is unclear. Methods: Serum GDF-15 concentrations in patients with heart failure ( Results: PhA showed a negative correlation with serum GDF-15 concentrations in total subjects. PhA showed a positive correlation with serum albumin (Alb) levels, hemoglobin (Hb) levels, estimated glomerular filtration rate (eGFR), and grip strength, and serum GDF-15 concentrations showed a negative correlation with serum Alb levels, Hb levels, eGFR, and grip strength. In multivariate regression analysis, after adjusting for age, PhA reflected the association with grip strength. For the presence or absence of muscle weakness measured by handgrip strength, in men, PhA had a cutoff value of 4.35 and an area under the curve (AUC) of 0.857, while GDF-15 had a cutoff value of 2012 pg/mL and an AUC of 0.773. In women, PhA had a cutoff value of 4.25 and an AUC of 0.804, while GDF-15 had a cutoff value of 1109 pg/mL and an AUC of 0.764. Conclusion: PhA showed a negative correlation with serum GDF-15 concentrations in hospitalized patients with cardiovascular disease. Both PhA and serum GDF-15 concentrations might be considered as a biomarker of sarcopenia or cachexia.
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Registered trials
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