ArticleFrontiers in medicine2026
Case Report: Modified therapeutic strategy for corrosive esophageal stricture-endoscopic balloon dilation combined with acellular dermal matrix transplantation.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Esophageal stricture caused by corrosive substance ingestion typically presents with dysphagia, chest pain, vomiting, and other discomfort, which severely impairs patients' quality of life. The treatment of corrosive esophageal stricture remains a challenging clinical issue that urgently needs to be addressed, and there have been no previous reports on the use of endoscopic balloon dilation combined with acellular dermal matrix transplantation for the treatment of corrosive esophageal stricture. Herein, we present a case of a 21-year-old male patient who developed severe panesophageal stricture following accidental ingestion of acidic toilet cleaner. Despite 13 prior endoscopic interventions, the patient suffered from persistent stricture recurrence and refractory symptoms. Subsequent treatment with combined endoscopic balloon dilation and acellular dermal matrix transplantation was performed successfully, leading to short-term significant symptomatic relief and improved quality of life. This case report demonstrates the feasibility and potential efficacy of the combined use of endoscopic balloon dilation and acellular dermal matrix transplantation for the management of severe panesophageal strictures induced by corrosive ingestion, providing a potential therapeutic option for this challenging clinical entity.
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